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Adaptations of the Hypothalamic Arcuate Nucleus in Response to Exercise and Hunger
(East Carolina University, 2018-05-02)
The arcuate nucleus of the hypothalamus serves as a critical node for regulation of mammalian energy balance with the ability to sense the status of many organ systems and exert control over effector arms that potently ...
Mitochondrial Oxidative Capacity In Human Skeletal Muscle: Association with Plasma Lactate Concentration
(East Carolina University, 2018-07-11)
ABSTRACT Background: Metabolic disease is a growing concern for public health. Obesity and Type II Diabetes are an epidemic and a phenotype for insulin resistance in human skeletal muscle. A reduced mitochondrial function ...
Shearwave elastography : a prospective study on short term changes in UCL health of college baseball pitchers
(East Carolina University, 2018-07-31)
The rate of ulnar collateral ligament (UCL) reconstruction surgery, or "Tommy John" surgery, has risen dramatically in baseball pitchers over the last decade. Throughout the baseball pitching motion, the UCL undergoes ...
AMP Deaminase 3 knockout mice and loss of mitochondrial proteins and enzyme activity during denervation atrophy
(East Carolina University, 2018-07-17)
Muscle atrophy leads to decrements in muscle function, partly attributable to decreased mitochondrial content. One controller of mitochondrial content is AMP-activated protein kinase (AMPK), which when bound by AMP activates ...
Progressive Loads in the Tibia During Exercise Related Activity
(East Carolina University, 2018-05-03)
Introduction: Bone stress injuries represent ~10% of injuries associated with sports and exercise and typically result in prolonged periods of recovery, costly diagnostic medical imaging, and exercise participation attrition. ...
THE RELATIONSHIP BETWEEN LACTATE, MITOCHONDRIA, AND PEROXISOMES IN HUMAN SKELETAL MUSCLE
(East Carolina University, 2018-05-03)
Human metabolism is a complex mechanism involving many interdependent parts. The purpose of this paper is to explore the relationship or lack thereof between lactate, mitochondria, and peroxisomes in human skeletal muscle. ...
Association Between Objectively Measured Physical Activity And Depression Symptoms
(East Carolina University, 2015)
Purpose: Previous studies examining the relationship between depression and physical activity have been epidemiological in nature and have measured physical activity subjectively. The purpose of the present study is to ...
Effects Of Extracellular Matrix Stiffness On Muscle Fiber Mechanotransduction Signaling In Aged Rats
(East Carolina University, 2015)
The loss of muscle mass with age, termed sarcopenia, is a common problem among the over 60 years-old population. Resistance training is often prescribed as treatment, but older adults have shown a reduced response to ...
Knee Joint Forces in Relation to Ground Surface Stiffness during Running
(East Carolina University, 2017-06-02)
Running shoes and surfaces have been developed to help enhance running efficiency and to reduce ground impacts by altering the total surface stiffness. However, to maintain running mechanics, an individual will increase ...
Maternal Attitudes and Behaviors and Weight Concerns of Gymnasts
(East Carolina University, 2017-07-18)
Weight concerns are highly prevalent for adolescent female aesthetic sport athletes, particularly gymnasts, and these concerns can have detrimental effects on overall health and well-being. Though the cause of these weight ...