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SKELETAL MUSCLE INSULIN SENSITIVITY AND DURATION OF TYPE 2 DIABETES MELLITUS
(East Carolina University, 2012)
Type 2 Diabetes Mellitus (T2DM) resolution following Roux-en Y gastric bypass (RYGB) surgery is reduced in patients with longer duration of T2DM and preliminary data suggest this may be mechanistically linked to lower ...
The Physiological and Pathological Role of Mitochondrial Calcium in the Diabetic Heart
(East Carolina University, 2011)
Diabetic patients are more susceptible to ischemia/reperfusion injury and cardiac dysfunction likely due alterations in mitochondrial calcium handling. The purpose of this work was to determine if redox-dependent changes ...
THE ROLE OF LONG-CHAIN ACYL-COENZYME A SYNTHETASE 1 (ACSL-1) IN LIPID METABOLISM IN HUMAN SKELETAL MUSCLE PRIMARY MYOTUBES.
(East Carolina University, 2011)
Obesity is considered a major health threat to the U.S. due to being a strong risk factor for developing type 2 diabetes and other metabolic diseases. The prevalence and severity of obesity is even greater among some ...
Evaluating Two Measures of Postural Stability in Response to Perturbations in People with Diabetic Neuropathy
(East Carolina University, 2015)
Diabetic neuropathy is a common complication of diabetes. It is characterized by a marked decrease in proprioception, particularly in the lower body. This reduced proprioception leads to an increase in falls risk in this ...
Effects of a high fat diet and/or overload on striated muscle structure, function, or metabolism
(East Carolina University, 2020-12-03)
Consumption of a high fat diet combined with physical inactivity is associated with many adverse health effects including obesity, insulin resistance/type 2 diabetes, and cardiovascular disease/myocardial infarction. The ...
Characterization of the glucose transporters responsible for mechanical overloadstimulated glucose uptake in mouse skeletal muscle
(East Carolina University, 8/5/2020)
Resistance exercise training is a recommended form of physical activity for people with type 2 diabetes due to its ability to increase skeletal muscle glucose uptake. Understanding how resistance training controls muscle ...