Search
Now showing items 1-9 of 9
Increased Antagonist Coactivation-Related Hamstring Torque Reduces Maximal Knee Extension Torque in Healthy Old Adults
(East Carolina University, 2010)
As humans age, the ability to produce maximal voluntary torque decreases due to muscle atrophy (sarcopenia) and it is also known that advancing age alters the neural control of voluntary movement. One manifestation of the ...
NEURAL MECHANISMS CONTRIBUTE TO THE AGE RELATED INCREASE IN METABOLIC COST OF GAIT
(East Carolina University, 2010)
Aging is associated with biomechanical and physiological changes in several organ systems, including neural changes of voluntary movement. One manifestation of age-related changes in neural control of gait is the increased ...
STRIDE LENGTH MANIPULATION IN YOUNG AND OLD ADULTS DURING LEVEL WALKING
(East Carolina University, 2010)
Physiological and neurological changes with healthy aging cause old adults to alter biomechanical gait strategies. Mechanical plasticity is an ambulatory strategy in which old adults rely on proximal musculature in ...
Cleaved Caspase-3 Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP-Activated Protein Kinase (AMPK) Activity
(East Carolina University, 2011)
In addition to suppressing protein synthesis and activating protein degradation in skeletal muscle and other cell types, 5'-AMP-activated protein kinase (AMPK) is known to stimulate nuclear apoptosis in non-muscle cells ...
Skeletal Muscle Forkhead Box 3A (FOXO3A) Response to Acute Resistance Exercise in Young and Old Men and Women : Relationship to Muscle Glycogen Content and 5'-AMP Activated Protein Kinase (AMPK) Activity
(East Carolina University, 2010)
In addition to suppressing protein synthesis, 5'-AMP-activated protein kinase (AMPK) stimulates muscle protein degradation through forkhead box transcription factor 3A (FOXO3A), known to promote transcription of mRNAs ...
Effects of Dietary Leucine Supplementation on Muscle Mass and Markers of Protein Degradation in Overloaded Skeletal Muscles of Young Adult and Aged Rats
(East Carolina University, 2011)
The hypertrophic response to overload in fast-twitch skeletal muscle is impaired in aged humans and rats, and upregulation of protein degradation pathways are hypothesized to be a contributing factor. Muscle growth occurs ...
Does AMP-Activated Protein Kinase Negatively Mediate Aged Fast-Twitch Skeletal Muscle Mass?
(East Carolina University, 2008-10)
The activity of 5'-adenosine monophosphate–activated protein kinase, a negative regulator of cell size, is up-regulated with age in resting and overloaded fast-twitch skeletal muscle but not slowtwitch muscle. Here, we ...
The relationship between visual steadiness and force steadiness in young and old adults
(East Carolina University, 2013)
Old adults exhibit a decrease in muscle force steadiness and visual capability compared to young adults. Many studies investigating force steadiness have used a visual target as the stimulus for modulating muscle force. ...
The Effect of Plantarflexor Strength Training on Gait Biomechanics in Healthy Old Adults
(East Carolina University, 2013)
Locomotion is an important and inherent part of daily life and is integral in maintaining an independent lifestyle, especially in older adults whose functional capacity has declined. Physiological changes with aging, ...