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RecA and RadA Proteins of Brucella abortus Do Not Perform Overlapping Protective DNA Repair Functions following Oxidative Burst
(East Carolina University, 2006-07)
Very little is known about the role of DNA repair networks in Brucella abortus and its role in pathogenesis. We investigated the roles of RecA protein, DNA repair, and SOS regulation in B. abortus. While recA mutants in ...
Raman spectroscopy: the gateway into tomorrow's virology
(East Carolina University, 2006-06-28)
In the molecular world, researchers act as detectives working hard to unravel the mysteries surrounding cells. One of the researchers' greatest tools in this endeavor has been Raman spectroscopy. Raman spectroscopy is a ...
Characterization of Bacteroides fragilis Hemolysins and Regulation and Synergistic Interactions of HlyA and HlyB
(East Carolina University, 2006-04)
This study describes the presence of 10 hemolysin orthologs in the genome of the opportunistic human anaerobic pathogen Bacteroides fragilis, which is currently classified as a nonhemolytic bacterium. The hemolysins were ...
Characterization of the Vaccinia Virus A35R Protein and Its Role in Virulence
(East Carolina University, 2006-01)
The vaccinia virus A35R gene is highly conserved among poxviruses and encodes a previously uncharacterized
hydrophobic acidic protein. Western blotting with anti-A35R peptide antibodies indicated that the protein
is ...
Characterization of the Primary Starch Utilization Operon in the Obligate Anaerobe Bacteroides fragilis: Regulation by Carbon Source and Oxygen
(East Carolina University, 2006-07)
The opportunistic pathogen Bacteroides fragilis is a commensal organism in the large intestine, where it utilizes both dietary and host-derived polysaccharides as a source of carbon and energy. In this study, a four-gene ...