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Analysis of the Zinc Finger Domain of TnpA, a DNA Targeting Protein Encoded by Mobilizable Transposon Tn4555
(East Carolina University, 2007-07)
The mobilizable transposon Tn4555, found in Bacteroides spp., is an important antibiotic resistance element encoding a broad spectrum beta-lactamase. Tn4555 is mobilized by conjugative transposons such as CTn341 which can ...
Biochemical and genetic analyses of a catalase from the anaerobic bacterium Bacteroides fragilis.
(East Carolina University, 1995-06)
A single catalase enzyme was produced by the anaerobic bacterium Bacteroides fragilis when cultures at late
log phase were shifted to aerobic conditions. In anaerobic conditions, catalase activity was detected ...
The Bacteroides mobilizable transposon Tn4555 integrates by a site-specific recombination mechanism similar to that of the gram-positive bacterial element Tn916
(East Carolina University, 1997-04)
The Bacteroides mobilizable transposon Tn4555 is a 12.2-kb molecule that encodes resistance to cefoxitin. Conjugal transposition is hypothesized to occur via a circular intermediate and is stimulated by coresident tetracycline ...
The Transfer Origin for Bacteroides Mobilizable Transposon Tn4555 Is Related to a Plasmid Family from Gram-Positive Bacteria
(East Carolina University, 1998-01)
Conjugal transfer of Bacteroides mobilizable transposon Tn4555 was examined with an Escherichia coli-based assay system. It was shown that mobilization required the cis-acting oriTTn region and that the Tn4555 mobATn gene ...
What Constitutes an Extended-Spectrum beta-lactamase?
(East Carolina University, 2002-02)
Aerobic-Type Ribonucleotide Reductase in the Anaerobe Bacteroides fragilis
(East Carolina University, 2002-02)
Bacteroides fragilis, a component of the normal intestinal flora, is an obligate anaerobe capable of long-term survival in the presence of air. Survival is attributed to an elaborate oxidative stress response that controls ...
Insertional activation of cepA leads to high-level beta-lactamase expression in Bacteroides fragilis clinical isolates.
(East Carolina University, 1994-07)
Bacteroides fragilis is an important opportunistic pathogen of humans and is resistant to many drugs commonly used to treat anaerobic infections, including P-lactams. A strain set comprised of B. fragilis isolates producing ...
Thioredoxin Reductase Is Essential for Thiol/Disulfide Redox Control and Oxidative Stress Survival of the Anaerobe Bacteroides fragilis
(East Carolina University, 2007-11)
Results of this study showed that the anaerobic, opportunistic pathogen Bacteroides fragilis lacks the
glutathione/glutaredoxin redox system and possesses an extensive number of putative thioredoxin (Trx)
orthologs. ...
Analysis of rRNA restriction fragment length polymorphisms from Bacteroides spp. and Bacteroides fragilis isolates associated with diarrhea in humans and animals.
(East Carolina University, 1992-04)
The Escherichia coli rRNA operon rrnB was used as a 32P-labeled hybridization probe in Southern blots of
genomic DNAs from representative strains of the saccharolytic, gram-negative, obligate anaerobes of the genus
Bacteroides. ...
The Redox-Sensitive Transcriptional Activator OxyR Regulates the Peroxide Response Regulon in the Obligate Anaerobe Bacteroides fragilis
(East Carolina University, 2000-09)
The peroxide response-inducible genes ahpCF, dps, and katB in the obligate anaerobe Bacteroides fragilis are
controlled by the redox-sensitive transcriptional activator OxyR. This is the first functional oxidative ...