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STRUCTURE-FUNCTION ANALYSIS OF A FAMILY OF BORRELIAL C1r INHIBITORS FROM LYME DISEASE AND RELAPSING FEVER SPIROCHETES
(East Carolina University, 2023-06-01)
The complement system is an ancient part of the innate immune system consisting of fluid-phase proteins that contribute to inflammation, homeostasis, and pathogen clearance. A group of vector-borne spirochetal pathogens ...