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A Study of the Abundance, Distribution, and Grazing Effects of Zooplankton in the Chlorophyll Maximum (CMAX) of the Neuse River Estuary, North Carolina
(East Carolina University, 2012)
Phytoplankton tend to accumulate in distinct zones referred to as chlorophyll maxima, or CMAX. A pronounced CMAX occurs in the Neuse River Estuary (NRE), North Carolina, where as much as over 60% of the estuary's phytoplankton ...
Sld5, A Subunit of the Heterotetrameric GINS Complex is Necessary for Normal Cell Cycle Progression and Genomic Stability
(East Carolina University, 2010)
Sld5 is one component of the GINS heterotetrameric complex essential to DNA replication. Specifically, GINS is known for its integral role during the G1 to S phase transition in the cell cycle. The GINS complex is comprised ...
EXPLORING THE BYSTANDER EFFECT FOLLOWING VERY LOW DOSE RADIATION
(East Carolina University, 2010)
Bystander effects are defined as the phenomenon in which unirradiated cells respond biologically when their neighbors are irradiated. The exact mechanisms of these cellular responses are still not known, especially in ...
Developing a Panel of Microsatellite Markers for Common Moorhen (Gallinula chloropus) as a Research Tool for Population Studies
(East Carolina University, 2013)
The common moorhen (Gallinula chloropus) sometimes exhibits brood parasitism - a parent manipulating a conspecific host to raise its offspring, relieving the parent of the encumbrance of parental investment. It has been ...
DISINTEGRIN-LIKE DOMAIN IN KSHV ENCODED gB IS A NECESSITY TO PROMOTE VIRUS LATENCY
(East Carolina University, 2011)
KSHV glycoprotein B (gB) is a lytic structural protein expressed on the envelope of mature virions and on the membrane of cells supporting lytic infection. Previous studies have identified that in addition to the role of ...
GILLNET CALIBRATION FOR SPINY DOGFISH ABUNDANCE ASSESSMENT
(East Carolina University, 2013)
Spiny dogfish (Squalus acanthias) is one of the most abundant species in the Northwest Atlantic however; the stocks collapsed in the late 1990s and were declared overfished April 3, 1998 by the Atlantic States Marine ...
Hypoxia and Serum Deprivation in Human Mesenchymal Stem Cells, and the Protective Role of Thymosin [Beta]-4
(East Carolina University, 2011)
Background: Current literature suggests nutrient deprivation and hypoxia affect human mesenchymal stem cell (hMSC) survival after cell transplantation. Wound-healing protein Thymosin [beta]-4 (T[beta]-4) has been shown ...
Effect of MicroRNA-34c on Regenerative Axon Growth in Dorsal Root Ganglion Neurons of the Peripheral Nervous System
(East Carolina University, 2011)
The peripheral nervous system is unique in its ability to regenerate axons after injury. Our lab previously assessed the miRNA expression levels of the regenerating sciatic nerve which indicated miR-34c up-regulation. ...
Spatio-Temporal Expression of Chondroitin Sulfate Antigens in Early Chick Pituitary and Thyroid
(East Carolina University, 2012)
The chondroitin sulfate antigens d1C4 and TC2 have been hypothesized to play a role in cartilage differentiation in the limb and early morphogenesis of the heart in chick embryos. The antibody d1C4 recognizes a native ...
The Role of Mitochondrial Biogenesis in Human Mesenchymal Stem Cell Differentiation and Acquisition of a Cardiac Phenotype
(East Carolina University, 2013)
Introduction: With an increased understanding of myocardial infarction, human mesenchymal stem cell (hMSC) transplantation therapies have shown promising results as a possible treatment for heart failure. However, little ...