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THE EFFECTS OF PRENATAL LEAD EXPOSURE ON THE DEVELOPMENT OF BIOMARKERS OF ALZHEIMER’S DISEASE
(2015-04)
While often well known for its adverse effects on memory, Alzheimer’s disease (AD) is also noteworthy for being the sixth leading cause of death in the United States. An estimated 5.2 million Americans had the disease as ...
MHC class I variation among wild, domestic and insular populations of the zebra finch (Taeniopygia guttata)
(East Carolina University, 2014)
The zebra finch (Taeniopygia guttata) is a passerine bird native to Australia and the Lesser Sunda Islands, with domesticated populations derived from each of these localities. The Lesser Sundas and domesticated zebra ...
RNA polymerase II CTD Evolutionary Diversity and Associated Protein Identification in Green and Red Algae
(East Carolina University, 2014)
In model eukaryotes, the C-terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II is composed of tandemly repeated heptads with the consensus sequence YSPTSPS. Both the core motif and tandem ...
Amazonian Amphibian Diversity Is Primarily Derived from Late Miocene Andean Lineages
(East Carolina University, 2009-03)
The Neotropics contains half of remaining rainforests and Earth’s largest reservoir of amphibian biodiversity. However, determinants of Neotropical biodiversity (i.e., vicariance, dispersals, extinctions, and radiations) ...
Are algal genes in nonphotosynthetic protists evidence of historical plastid endosymbioses?
(East Carolina University, 2009)
Background: How photosynthetic organelles, or plastids, were acquired by diverse eukaryotes is among the most hotly debated topics in broad scale eukaryotic evolution. The history of plastid endosymbioses commonly is ...
Adaptive evolution of genes underlying schizophrenia
(East Carolina University, 2007-11-22)
Schizophrenia poses an evolutionary-genetic paradox because it exhibits strongly negative fitness effects and high heritability, yet it persists at a prevalence of approximately 1% across all human cultures. Recent theory ...
Photofrin-Mediated Electroporation-Assisted Photodynamic Therapy of MCF-7 Human Breast Cancer and B16-F10 Mouse Melanoma Cells
(East Carolina University, 2011)
Photodynamic therapy is a relatively new player on the field of cancer treatment that involves the injection of a nontoxic light-sensitive drug followed by light excitation, creating reactive oxygen species that cause ...
Nicotine Controlof Germline Cell Fate in Caenorhabditis elegans
(2015-05)
Nicotine dependence is the single largest cause of preventable death in the world, claiming 480,000 lives each year in the US alone, including those caused by secondhand smoke. In this study, we investigated the biological ...
Characterization of Extracellular Polymeric Substances from Acidophilic Microbial Biofilms
(East Carolina University, 2010-05)
We examined the chemical composition of extracellular polymeric substances (EPS) extracted from two natural microbial pellicle biofilms growing on acid mine drainage (AMD) solutions. The EPS obtained from a mid-developmental-stage ...
Food and Feeding of Young Striped Bass in the Lower Roanoke River and Western Albemarle Sound, North Carolina, 1990-1991
(East Carolina University, 1992-07)
This study was conducted during the springs of 1990 and 1991 to provide information on possible causes of the decline in the Roanoke/Albemarle striped bass stock. Striped bass in this system migrate approximately 130 miles ...