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EGID: an ensemble algorithm for improved genomic island detection in genomic sequences
(2011)
Genomic islands (GIs) are genomic regions that are originally transferred from other organisms. The detection of genomic islands in genomes can lead to many applications in industrial, medical and environmental contexts. ...
Cdc6 expression represses E-cadherin transcription and activates adjacent replication origins
(2011-12)
E-cadherin (CDH1) loss occurs frequently in carcinogenesis, contributing to invasion and metastasis. We observed that mouse and human epithelial cell lines overexpressing the replication licensing factor Cdc6 underwent ...
Arthropod Phylogenetics in Light of Three Novel Millipede (Myriapoda: Diplopoda) Mitochondrial Genomes with Comments on the Appropriateness of Mitochondrial Genome Sequence Data for Inferring Deep Level Relationships
(2013)
Background
Arthropods are the most diverse group of eukaryotic organisms, but their phylogenetic relationships are poorly understood. Herein, we describe three mitochondrial genomes representing orders of millipedes for ...
Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback
(2015-12)
Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ...
Comprehensive analysis of TCP transcription factors and their expression during cotton () fiber early development
(2016-02)
TCP proteins are plant-specific transcription factors implicated to perform a variety of physiological functions during plant growth and development. In the current study, we performed for the first time the comprehensive ...
Digits Lost or Gained? Evidence for Pedal Evolution in the Dwarf Salamander Complex ( Plethodontidae)
(2012)
Change in digit number, particularly digit loss, has occurred repeatedly over the evolutionary history of tetrapods. Although digit loss has been documented among distantly related species of salamanders, it is relatively ...
Experimental design and statistical rigor in phylogenomics of horizontal and endosymbiotic gene transfer
(2011)
A growing number of phylogenomic investigations from diverse eukaryotes are examining conflicts among gene trees as evidence of horizontal gene transfer. If multiple foreign genes from the same eukaryotic lineage are found ...
MicroRNA Expression Analysis in the Cellulosic Biofuel Crop Switchgrass () under Abiotic Stress
(2012)
Switchgrass has increasingly been recognized as a dedicated biofuel crop for its broad adaptation to marginal lands and high biomass. However, little is known about the basic biology and the regulatory mechanisms of gene ...
Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes
(2014-08)
Type 2 diabetes (T2D) is more prevalent in African Americans than in Europeans. However, little is known about the genetic risk in African Americans despite the recent identification of more than 70 T2D loci primarily by ...
Differential gene expression and alternative splicing in insect immune specificity
(2014-11)
Background
Ecological studies routinely show genotype-genotype interactions between insects and their parasites. The mechanisms behind these interactions are not clearly understood. Using the bumblebee Bombus terrestris ...