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Genome sequencing and analysis of the paclitaxel-producing endophytic fungus NRRL 62431
(2014)
Background
Paclitaxel (Taxol™) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted to the Taxus species until it was discovered in Taxomyces andreanae, ...
Ancient gene transfer from algae to animals: Mechanisms and evolutionary significance
(2012)
Background
Horizontal gene transfer (HGT) is traditionally considered to be rare in multicellular eukaryotes such as animals. Recently, many genes of miscellaneous algal origins were discovered in choanoflagellates. ...
Genome-Wide Functional Analysis of the Cotton Transcriptome by Creating an Integrated EST Database
(2011)
A total of 28,432 unique contigs (25,371 in consensus contigs and 3,061 as singletons) were assembled from all 268,786 cotton ESTs currently available. Several in silico approaches [comparative genomics, Blast, Gene Ontology ...
Root parasitic plant and shoot parasitic plant obtained Brassicaceae-specific genes by horizontal gene transfer
(2014)
Background
Besides gene duplication and de novo gene generation, horizontal gene transfer (HGT) is another important way of acquiring new genes. HGT may endow the recipients with novel phenotypic traits that are important ...
MicroRNA Expression Analysis in the Cellulosic Biofuel Crop Switchgrass () under Abiotic Stress
(2012)
Switchgrass has increasingly been recognized as a dedicated biofuel crop for its broad adaptation to marginal lands and high biomass. However, little is known about the basic biology and the regulatory mechanisms of gene ...
The scale and evolutionary significance of horizontal gene transfer in the choanoflagellate
(2013-10)
Background
It is generally agreed that horizontal gene transfer (HGT) is common in phagotrophic protists. However, the overall scale of HGT and the cumulative impact of acquired genes on the evolution of these organisms ...
Deep Sequencing Reveals Transcriptome Re-Programming of Cells to the Elicitation with Methyl Jasmonate
(2013)
Background
Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ...
Evidence for acquisition of virulence effectors in pathogenic chytrids
(2011)
Background
The decline in amphibian populations across the world is frequently linked to the infection of the chytrid fungus Batrachochytrium dendrobatidis (Bd). This is particularly perplexing because Bd was only recently ...