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Versican Expression during Synovial Joint Morphogenesis
(East Carolina University, 2007-09)
The extracellular matrix (ECM) plays a critical role in governing cell behavior and phenotype during limb skeletogenesis. Chondroitin sulfate proteoglycans (Cspgs) are highly expressed in the ECM of precartilage mesenchymal ...
Inbreeding Depression and Mixed Mating in Leptosiphon jepsonii: A Comparison of Three Populations
(East Carolina University, 2006-08)
Background and Aims: Inbreeding depression is thought to play a central role in the evolution and maintenance of cross-fertilization. Theory indicates that inbreeding depression can be purged with self-fertilization, ...
RDX Induces Aberrant Expression of MicroRNAs in Mouse Brain and Liver
(East Carolina University, 2009-02)
Background: Although microRNAs (miRNAs) have been found to play an important role in many biological and metabolic processes, their functions in animal response to environmental toxicant exposure are largely unknown. ...
Posttranslational modifications in the CP43 subunit of photosystem II
(East Carolina University, 2002-11-12)
Photosystem II (PSII) catalyzes the light-driven oxidation of water
and the reduction of plastoquinone; the oxidation of water occurs at a cluster of four manganese. The PSII CP43 subunit functions in light ...
RDX and miRNA Expression: Zhang and Pan Respond
(East Carolina University, 2009-03)
Concerted gene recruitment in early plant evolution
(East Carolina University, 2008-07)
Background: Horizontal gene transfer occurs frequently in prokaryotes and unicellular eukaryotes. Anciently acquired genes, if retained among descendants, might significantly affect the long-term evolution of the recipient ...
The evolution of parental care and egg size: a comparative analysis in frogs
(East Carolina University, 2006-03-22)
The evolution of parental care and egg size has attracted considerable attention and theoretical debate. Several different hypotheses have been proposed concerning the trajectories of parental care and egg size evolution ...
Molecular and Cellular Biology Animations: Development and Impact on Student Learning
(East Carolina University, 2005)
Educators often struggle when teaching cellular and molecular processes because typically they have only two-dimensional tools to teach something that plays out in four dimensions. Learning research has demonstrated that ...
Pleistocene glacial refugia across the Appalachian Mountains and coastal plain in the millipede genus Narceus: Evidence from population genetic, phylogeographic, and paleoclimatic data
(East Carolina University, 2009-01-30)
Background: Species that are widespread throughout historically glaciated and currently nonglaciated areas provide excellent opportunities to investigate the role of Pleistocene climatic change on the distribution of North ...
Functional Unit of the RNA Polymerase II C-Terminal Domain Lies within Heptapeptide PairsÂ
(East Carolina University, 2004-06)
Unlike all other RNA polymerases, the largest subunit (RPB1) of eukaryotic DNA-dependent RNA polymerase II (RNAP II) has a C-terminal domain (CTD) comprising tandemly repeated heptapeptides with the consensus sequence ...