Browsing Other Campus Research by Title
Now showing items 206-225 of 1012
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Customer Reviews Analysis With Deep Neural Networks for E-Commerce Recommender Systems
(2019-08-26)An essential prerequisite of an effective recommender system is providing helpful information regarding users and items to generate high-quality recommendations. Written customer review is a rich source of information ... -
Cutaneous adverse reactions in B-RAF positive metastatic melanoma following sequential treatment with B-RAF/MEK inhibitors and immune checkpoint blockade or vice versa. A single-institutional case-series
(2018-12-16)Background With the advent of immune-checkpoint inhibitors and targeted treatments (TT), there have been unprecedented response rates and survival in advanced melanoma, but the optimal sequencing of these two treatments ... -
Cutaneous melanoma: From pathogenesis to therapy (Review)
(2018-02-27)In less than 10 years, melanoma treatment has been revolutionized with the approval of tyrosine kinase inhibitors and immune checkpoint inhibitors, which have been shown to have a significant impact on the prognosis of ... -
The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi
(2014-05-01)In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B. burgdorferi must be ... -
Cytokine-neuroantigen fusion proteins as a new class of tolerogenic, therapeutic vaccines for treatment of inflammatory demyelinating disease in rodent models of multiple sclerosis
(2012-08-20)Myelin-specific induction of tolerance represents a promising means to modify the course of autoimmune inflammatory demyelinating diseases such as multiple sclerosis (MS). Our laboratory has focused on a novel preclinical ... -
Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells
(2014)Hepatocellular carcinoma (HCC) is characterized by limited response to current drug therapies. Here, we report that SC66, a novel AKT inhibitor, reduced cell viability in a dose- and time-dependent manner, inhibited ... -
Cytotoxic and Pathogenic Properties of Klebsiella oxytoca Isolated from Laboratory Animals
(2014-07)Klebsiella oxytoca is an opportunistic pathogen implicated in various clinical diseases in animals and humans. Studies suggest that in humans K. oxytoca exerts its pathogenicity in part through a cytotoxin. However, cytotoxin ... -
Daily precipitation distributions over the intra-Americas sea and their interannual variability
(2012-05-30)The seasonal (March to October) and interannual variability of the cumulative distribution function (CDF) of precipitation is examined for Meso-America, the eastern Pacific and western Atlantic, commonly referred to as the ... -
Damage control surgery: It's evolution over the last 20 years
(2012-03-15)In less than twenty years, what began as a concept for the treatment of exsanguinating truncal trauma patients has become the primary treatment model for numerous emergent, life threatening surgical conditions incapable ... -
Decarboxylative and dehydrative coupling of dienoic acids and pentadienyl alcohols to form 1,3,6,8-tetraenes
(2017-02-28)Dienoic acids and pentadienyl alcohols are coupled in a decarboxylative and dehydrative manner at ambient temperature using Pd(0) catalysis to generate 1,3,6,8-tetraenes. Contrary to related decarboxylative coupling ... -
Decreased CD8+CD28+/CD8+CD28– T cell ratio can sensitively predict poor outcome for patients with complicated Crohn disease
(2017-06)Crohn disease (CD) with complications such as penetrating, stricturing, and perianal disease is called complicated CD. The aim of this study is to test the efficiency with which the CD8+CD28+/CD8+CD28– cell balance can ... -
Deep sequencing reveals important roles of microRNAs in response to drought and salinity stress in cotton
(2015-02)Drought and salinity are two major environmental factors adversely affecting plant growth and productivity. However, the regulatory mechanism is unknown. In this study, the potential roles of small regulatory microRNAs ... -
Deep Sequencing Reveals Transcriptome Re-Programming of Taxus × media Cells to the Elicitation with Methyl Jasmonate
(2013-04-30)Background Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ... -
Dehiscence and embolization of CorMatrix tricuspid valve replacement in the setting of infective endocarditis: a case report
(2018-01-31)Background: Due to increased morbidity and mortality, prosthetic valve infective endocarditis (IE) with dehiscence requires urgent intervention. Early identification and therapy may prevent embolization. Case summary: A ... -
Deletion of BmoR affects the expression of genes related to thiol/disulfide balance in Bacteroides fragilis
(2018-09-26)Bacteroides fragilis, an opportunistic pathogen and commensal bacterium in the gut, is one the most aerotolerant species among strict anaerobes. However, the mechanisms that control gene regulation in response to oxidative ... -
Deletion of Macrophage Vitamin D Receptor Promotes Insulin Resistance and Monocyte Cholesterol Transport to Accelerate Atherosclerosis in Mice
(2015)Intense effort has been devoted to understanding predisposition to chronic systemic inflammation because it contributes to cardiometabolic disease. We demonstrate that deletion of the macrophage vitamin D receptor (VDR) ... -
Delineation and mapping of coastal shark habitat within a shallow lagoonal estuary
(2018-04-12)Estuaries function as important nursery and foraging habitats for many coastal species, including highly migratory sharks. Pamlico Sound, North Carolina, is one of the largest estuaries in the continental United States and ... -
Desiccation tolerance in Acinetobacter baumannii is mediated by the two-component response regulator BfmR
(2018-10-11)For the opportunistic pathogen Acinetobacter baumannii, desiccation tolerance is thought to contribute significantly to the persistence of these bacteria in the healthcare environment. We investigated the ability of A. ... -
Design of a prospective, multicenter, global, cohort study of electromagnetic navigation bronchoscopy
(2016-04-26)Background: Electromagnetic navigation bronchoscopy (ENB) procedures allow physicians to access peripheral lung lesions beyond the reach of conventional bronchoscopy. However, published research is primarily limited to ...