Browsing Other Campus Research by Title
Now showing items 626-645 of 1103
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MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex
(2012-04)Recently, strategies for acute myeloid leukemia (AML) therapy have been developed that target anti-apoptotic BCL2 family members using BH3-mimetic drugs such as ABT-737. Though effective against BCL2 and [BCL-X.sub.L], ... -
MELPF version 1: Modeling Error Learning based Post-Processor Framework for Hydrologic Models Accuracy Improvement
(2019-09-23)This paper studies how to improve the accuracy of hydrologic models using machine-learning models as postprocessors and presents possibilities to reduce the workload to create an accurate hydrologic model by removing the ... -
MELPF Version 1: Modeling Error Learning Based Post-Processor Framework for Hydrologic Models Accuracy Improvement
(2019-09-23)This paper studies how to improve the accuracy of hydrologic models using machine-learning models as postprocessors and presents possibilities to reduce the workload to create an accurate hydrologic model by removing the ... -
Memory of Germinant Stimuli in Bacterial Spores
(2015-11)Bacterial spores, despite being metabolically dormant, possess the remarkable capacity to detect nutrients and other molecules in their environment through a biochemical sensory apparatus that can trigger spore germination, ... -
A Mentor-Led Text-Messaging Intervention Increases Intake of Fruits and Vegetables and Goal Setting for Healthier Dietary Consumption among Rural Adolescents in Kentucky and North Carolina, 2017
(2019-03-11)Text-messaging interventions hold promise for successful weight loss interventions. However, there is limited research on text-messaging interventions to improve dietary intake among rural adolescents, who are at greater ... -
Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system
(2011-06-20)Adipocyte infiltration of the musculoskeletal system is well recognized as a hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a benign storage site for surplus lipid or play a role ... -
Metagenomic Evidence for H2 Oxidation and H2 Production by Serpentinite-Hosted Subsurface Microbial Communities
(2012-01-06)Among civilian academic physicians, having a mentor is associated with greater job satisfaction. Whether this is true for military physicians is unknown. We sought to examine whether having a mentor is associated with ... -
Methods for assessing mitochondrial function in diabetes
(2013-03-14)A growing body of research is investigating the potential contribution of mitochondrial function to the etiology of type 2 diabetes. Numerous in vitro, in situ, and in vivo methodologies are available to examine various ... -
A Micro-Thermal Sensor for Focal Therapy Applications
(2016-02-26)There is an urgent need for sensors deployed during focal therapies to inform treatment planning and in vivo monitoring in thin tissues. Specifically, the measurement of thermal properties, cooling surface contact, tissue ... -
MicroRNA expression analysis in the cellulosic biofuel crop switchgrass (panicum virgatum) under abiotic stress
(2012-03-28)Switchgrass has increasingly been recognized as a dedicated biofuel crop for its broad adaptation to marginal lands and high biomass. However, little is known about the basic biology and the regulatory mechanisms of gene ... -
MicroRNA expression profiles during cotton (Gossypium hirsutum L) fiber early development
(2017-03-22)The role of microRNAs (miRNAs) during cotton fiber development remains unclear. Here, a total of 54 miRNAs belonging to 39 families were selected to characterize miRNA regulatory mechanism in eight different fiber development ... -
MicroRNA profiling in the left atrium in patients with non-valvular paroxysmal atrial fibrillation
(2015)identifying miRNAs that were significantly associated with non-valvular paroxysmal AF. Methods: The RNA samples were isolated from healthy controls (n = 5) and patients with atrial fibrillation (n = 8). To confirm the ... -
MicroRNA-431 regulates axon regeneration in mature sensory neurons by targeting the Wnt antagonist Kremen1
(2013-10-24)MicroRNAs are small, non-coding RNAs that function as key post-transcriptional regulators in neural development, brain function and neurological diseases. Growing evidence indicates that microRNAs are also important mediators ... -
Microscale structural changes of individual fibrin fibers during fibrinolysis
(2022-01-07)Fibrinolysis is the enzymatic digestion of fibrin, the primary structural component in blood clots. Mechanisms of fibrin fiber digestion during lysis have long been debated and obtaining detailed structural knowledge of ... -
Microvascular Endothelial Dysfunction in Sedentary, Obese Humans Is Mediated by NADPH Oxidase Influence of Exercise Training
(2016)Objective—The objectives of this study were to determine the impact of in vivo reactive oxygen species (ROS) on microvascular endothelial function in obese human subjects and the efficacy of an aerobic exercise intervention ... -
Millipede taxonomy after 250 years: classification and taxonomic practices in a mega-diverse yet understudied arthropod group.
(2012-03-15)BACKGROUND: The arthropod class Diplopoda is a mega-diverse group comprising >12,000 described millipede species. The history of taxonomic research within the group is tumultuous and, consequently, has yielded a questionable ... -
miRNA-23a/27a attenuates muscle atrophy and renal fibrosis through muscle-kidney crosstalk
(2018-03-26)Background The treatment of muscle wasting is accompanied by benefits in other organs, possibly resulting from muscle– organ crosstalk. However, how the muscle communicates with these organs is less understood. Two microRNAs ... -
miRNA-36 inhibits KSHV, EBV, HSV-2 infection of cells via stifling expression of interferon induced transmembrane protein 1 (IFITM1)
(2017-12-21)Kaposi’s sarcoma-associated herpesvirus (KSHV) is etiologically associated with all forms of Kaposi’s sarcoma worldwide. Little is currently known about the role of microRNAs (miRNAs) in KSHV entry. We recently demonstrated ... -
The mismatch between current statistical practice and doctoral training in ecology
(2016-08-17)Ecologists are studying increasingly complex and important issues such as climate change and ecosystem services. These topics often involve large data sets and the application of complicated quantitative models. We evaluated ... -
Mismatched anti-predator behavioral responses in predator-naïve larval anurans
(2015)Organisms are adept at altering behaviors to balance the tradeoff between foraging and predation risk in spatially and temporally shifting predator environments. In order to optimize this tradeoff, prey need to be able to ...