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Impact of body mass index on the incidence and severity of post-endoscopic retrograde cholangiopancreatography pancreatitis
(2019-03-12)
Background: Pancreatitis is a potential major complication after endoscopic retrograde
cholangiopancreatography (post-ERCP pancreatitis; PEP). Obesity has been associated with
increased severity of acute pancreatitis. ...
How many steps/day are enough? For older adults and special populations
(2011-07-28)
Older adults and special populations (living with disability and/or chronic illness that may limit mobility and/or physical endurance) can benefit from practicing a more physically active lifestyle, typically by increasing ...
Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells
(2017-01-27)
Acidosis commonly exists in the tissue microenvironment of various pathophysiological conditions such as tumors, inflammation, ischemia, metabolic disease, and respiratory disease. For instance, the tumor microenvironment ...
Is the genetic landscape of the deep subsurface biosphere affected by viruses?
(2011-11-09)
Viruses are powerful manipulators of microbial diversity, biogeochemistry, and evolution in the marine environment. Viruses can directly influence the genetic capabilities and the fitness of their hosts through the use of ...
Analysis of the Germination of Individual Clostridium sporogenes Spores with and without Germinant Receptors and Cortex-Lytic Enzymes
(2017-10-25)
The Gram-positive spore-forming anaerobe Clostridium sporogenes is a significant cause of food spoilage, and it is also used as a surrogate for C. botulinum spores for testing the efficacy of commercial sterilization. C. ...
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
(2011-07-01)
Elucidating the response of breast cancer cells to chemotherapeutic and hormonal based drugs is clearly important as these are frequently used therapeutic approaches. A signaling pathway often involved in chemo- and ...
Ages and Stages Questionnaire: a global screening scale | Ages and Stages Questionnaire: una escala de evaluación global
(2017-01-30)
Abstract With standardized screening tools, research studies have shown that developmental disabilities can be detected reliably and with validity in children as young as 4 months of age by using the instruments such as ...
An Expanded Multi-scale Monte Carlo Simulation Method for Personalized Radiobiological Effect Estimation in Radiotherapy: a feasibility study
(2017-03-21)
A novel and versatile “bottom-up” approach is developed to estimate the radiobiological effect of clinic
radiotherapy. The model consists of multi-scale Monte Carlo simulations from organ to cell levels. At cellular level, ...
Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment
(2017-08-24)
Using the principle of antibody-drug conjugates that deliver highly potent cytotoxic agents to
cancer cells for cancer therapy, we here report the synthesis of antisense-oligonucleotides (ASO) and thyroid hormone T3 ...
HIV screening and awareness survey for pregnant women in a remote area in Xinjiang Uyghur autonomous region of China
(2011-11-30)
The number of people infected with human immunodeficiency virus (HIV) in China has increased in recent years. HIV screening for pregnant women was performed in a remote area in Xinjiang, as an effort to promote universal ...