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Relief of dysphagia due to advanced achalasia by endoscopic creation of an esophagogastric bypass anastomosis through an epiphrenic diverticulum
(2017-05-18)
An 85-year-old man with long-standing dysphagia and multiple admissions for aspiration pneumonia was referred for evaluation.
THE 2016 MODEL OF THE CLINICAL PRACTICE OF EMERGENCY MEDICINE
(2017-06)
Emergency medicine (EM) has a scientifically derived and commonly accepted description of the domain of its clinical practice. That document, “The Model of the Clinical Practice of Emergency Medicine” (EM Model), was ...
Oral microbe-host interactions: influence of β-glucans on gene expression of inflammatory cytokines and metabolome profile
(2017-03-07)
Background: The aim of this study was to evaluate the effects of β-glucan on the expression of inflammatory mediators and metabolomic profile of oral cells [keratinocytes (OBA-9) and fibroblasts (HGF-1) in a dual-chamber ...
Nearshore mixing and nutrient delivery along the western Antarctic Peninsula
(2017-10)
The surface waters of the Southern Ocean play a key role in the global climate and carbon cycles by
promoting growth of some of the world’s largest phytoplankton blooms. Several studies have emphasized the
importance of ...
Pathology Informatics Essentials for Residents: A Flexible Informatics Curriculum Linked to Accreditation Council for Graduate Medical Education Milestones
(2017-01)
Context.—Recognition of the importance of informatics to the practice of pathology has surged. Training residents in pathology informatics has been a daunting task for most residency programs in the United States because ...
Una adelfa en tierras extrañas emblemática y misoginia en la "Comedia famosa de los guanches de Tenerife y conquista de Canaria
(2017)
In his play Los guanches de Tenerife Lope de Vega resorts to one of the emblems included in his friend Hernando de Soto’s Emblemas moralizadas (1599) to dramatize the encounter between Guanches and Spaniards and to represent ...
Plant genome editing with TALEN and CRISPR
(2017-04-24)
Genome editing promises giant leaps forward in advancing biotechnology, agriculture, and basic research. The process relies on the use of sequence specific nucleases (SSNs) to make DNA double stranded breaks at user defined ...
Novel Pelagic Iron-Oxidizing Zetaproteobacteria from the Chesapeake Bay Oxic–Anoxic Transition Zone
(2017-07-18)
Chemolithotrophic iron-oxidizing bacteria (FeOB) could theoretically inhabit any environment where Fe(II) and O2 (or nitrate) coexist. Until recently, marine Fe-oxidizing Zetaproteobacteria had primarily been observed in ...
N6-methyladenosine is required for the hypoxic stabilization of specific mRNAs
(2017-09)
Post-transcriptional regulation of mRNA during oxygen deprivation, or hypoxia, can affect the survivability of cells. Hypoxia has been shown to increase stability of a subset of ischemia-related mRNAs, including VEGF. RNA ...
Neuron-derived transthyretin modulates astrocytic glycolysis in hormone-independent manner
(2017-11-20)
It has been shown that neurons alter the expression of astrocytic metabolic enzymes by secretion of until now unknown molecule(s) into extracellular fluid. Here, we present evidence that neuron-derived transthyretin (TTR) ...