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Association of Lowering Low‐Density Lipoprotein Cholesterol With Contemporary Lipid‐Lowering Therapies and Risk of Diabetes Mellitus: A Systematic Review and Meta‐Analysis
(2019-04-02)
Background
The relationship between lowering LDL (low‐density lipoprotein) cholesterol with contemporary lipid‐lowering therapies and incident diabetes mellitus (DM) remains uncertain.
Methods and Results
Thirty‐three ...
Association Between Health Literacy, Electronic Health Literacy, Disease-Specific Knowledge, and Health-Related Quality of Life Among Adults With Chronic Obstructive Pulmonary Disease: Cross-Sectional Study
(2019-06-06)
Background: Despite the relatively high prevalence of low health literacy among individuals living with chronic obstructive pulmonary disease (COPD), limited empirical attention has been paid to the cognitive and health ...
Construction of realistic hybrid computational fetal phantoms from radiological images in three gestational ages for radiation dosimetry applications
(2019-10-10)
Radiation exposure and associated radiation risks are major concerns for fetal development for
pregnant patients who undergo radiation therapy or diagnostic imaging procedures. In order to
accurately estimate the radiation ...
Effects of Stathmin 1 Gene Knockout on Behaviors and Dopaminergic Markers in Mice Exposed to Social Defeat Stress
(2019-08-26)
Stathmin (STMN), a microtubule-destabilizing factor, can regulate fear, anxiety, and learning. Social defeat stress (SDS) has detrimental effects on mental health and increases the risk of various psychiatric diseases. ...
Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein
(2019-08-08)
The C-terminal binding protein (CtBP) is an NADH-dependent dimeric family of nuclear proteins that scaffold interactions between transcriptional regulators and chromatin-modifying complexes. Its association with poor ...
Esophageal perforation secondary to malignant gastric outlet obstruction: a case report
(2019-02-19)
Background
Esophageal perforation is a rare presenting sign of gastric cancer. To date, only nine case reports of this phenomenon have been previously published.
Case presentation
Esophageal perforation was diagnosed ...
An evolutionary perspective on marine invasions
(2019-12-10)
Species distributions are rapidly changing as human globalization increasingly moves organisms to novel environments. In marine systems, species introductions are the result of a number of anthropogenic mechanisms, notably ...
Cap-Independent mRNA Translation in Germ Cells
(2019-01-04)
Cellular mRNAs in plants and animals have a 50-cap structure that is accepted as the
recognition point to initiate translation by ribosomes. Consequently, it was long assumed that the
translation initiation apparatus was ...
Burden of Cardiovascular Risk Factors Over Time and Arterial Stiffness in Youth With Type 1 Diabetes Mellitus: The SEARCH for Diabetes in Youth Study
(2019-07-02)
Background: The incidence of type 1 diabetes mellitus (T1DM) in children is increasing, resulting in higher burden of cardiovascular diseases due to diabetes mellitus–related vascular dysfunction.
Methods and Results: We ...
Calibrating TrueBeam jaws by considering collimator walk out to improve the dose uniformity at abutting field junctions
(2019-01-11)
Jaw positions on a linear accelerator are calibrated to have accurate field size values over the range of jaw positions and to have excellent junctions when matching fields. It is sufficient to have field size accuracy on ...