Browsing Honors College by Title
Now showing items 455-474 of 959
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Insight Into the Location of DNA Xenobiotic Damage by Mass Spectrometry
(2014)Damage to DNA by a bioactivated xenobiotic typically occurs at specific sites within the genome, called hotspots. An example of this is benzo[a]-pyrene (BP), a xenobiotic that enters the body via cigarette smoking. ... -
Installation of Metal-Binding Functionality at Lysine Residues via Azide-Alkyne "Click Chemistry"
(2015-04-29)A novel non-natural amino acid designed to bind divalent metal ions, dubbed Lys(PYRIT), was prepared in a “click reaction” by treating Fmoc-Lys(N3)-OH with 2-ethynylpyridine and Cu(I). It was incorporated into a 12-residue ... -
INSULATION IN RESIDENTIAL HOME BUILDINGS: COST COMPARISON OF TRADITIONAL AND HEMP BUILDING INSULATION
(East Carolina University, 2022-05-04)The materials from harvested from hemp plants have become an increasingly popular material for building across the world based on its availability and sustainable properties. Hemp is being used as an alternative insulation ... -
Insulin Stimulated Lactate Production
(2014)It has been shown that Type 2 diabetic patients who undergo Roux-en-Y Gastric Bypass surgery (RYGB) show a decrease in muscle lactate production, liver glucose production and pancreatic insulin secretion. To explain these ... -
INTERACTION BETWEEN HTLV-1 BASIC LEUCINE ZIPPER FACTOR (HBZ) AND HOST CELL PROTEINS PROMOTES CELLULAR TRANSFORMATION
(2016-04-26)Human T-cell Leukemia Virus Type 1 (HTLV-1) is a complex retrovirus which preferentially infects CD4+ T-cells. Endemic to Japan, regions of South America, Africa, and the Caribbean, HTLV-1 is transmitted through breastfeeding, ... -
INTERSECTIONALITY AND BURNOUT IN MEDICAL RESIDENCY PROGRAMS: NARRATIVES ACROSS THE NATION
(East Carolina University, 2023-12-15)Burnout impacts up to 75% of medical residents in the United States. Although nearly half of active medical residents in the U.S. identify as individuals with intersecting underrepresented identities including racial, ... -
Into the Fire!
(East Carolina University, 2022-05-06)I don’t know what the future holds for me. I don’t know where I‘m headed, what I will do, or even what I want out of this life. My life, much like my artwork, is highly influenced by my setting and by those surrounding me. ... -
Intracardiac Dopamine Receptor 1 and 3 Expression in Angiotensin II - Induced Hypertension and Myocardial Infarction
(East Carolina University, 2023-05-03)Dopamine receptors have been extensively studied in the central nervous system as they are vital to maintaining cognition, motor skills, and the reward system (1). Recently, literature has uncovered the prevalence of these ... -
Introduction of Gender Affirming Care to the APRN Curriculum
(East Carolina University, 2023-04-26)The Advanced Practice Registered Nursing (APRN) curriculum is the source of a nationwide issue regarding its severe lack of education on gender affirming care. This research will be performed on those who are pursuing a ... -
Investigating and Sharing the Stories of Our Community's Heroes
(2015)This short documentary shines a light on Greenville Fire-Rescue, its daily operations, and the men and women who serve the Greenville community from behind the scenes. Greenville Fire-Rescue follows a nationwide trend in ... -
Investigating Co-planning and Co-teaching in Higher Education Statistics
(East Carolina University, 2023-12-14)Co-planning and co-teaching are relatively new in comparison to the field of education. Initially, it was used as a method of collaboration between general education teachers and special education teachers. In recent years, ... -
Investigating Fraud and Strategies to Decrease Fraud within Youth Sports Organizations
(East Carolina University, 2023-12-06)Occupation fraud is one of the most common financial crimes. Occupational fraud is defined as fraud committed by individuals against the organization that employs them. Most people that commit occupational fraud have access ... -
Investigating the causes of hatching failure of Eastern Bluebird eggs: A possible role for heat shock proteins
(East Carolina University, 2023-05-03)Eastern Bluebirds (Sialia sialis) studied for 13 years at East Carolina University’s West Research Campus have shown declines in reproductive success via hatching failure in recent years. The purpose of my research is to ... -
Investigating the Impact of Mettl16 Cellular Localization on RNA Binding Preferences
(East Carolina University, 2019-05-14)Recently, mRNA modification by N6-methyladenosine (m6A) has been shown to be involved in post-transcriptional regulation processes including mRNA stability, splicing and promotion of translation. Accordingly, the mRNA ... -
INVESTIGATING THE MOLECULAR CONTROL OF ECDYSONE RESPONSE GENE, E74, IN THE DROSOPHILA OVARY.
(East Carolina University, 2017-05-05)Oogenesis is the process by which an egg develops from precursor cells in the ovary. This process has been widely studied; however, many of the molecular mechanisms that regulate oocyte development and growth remain unclear. ... -
Investigating the Relationship between Environmental Lead Exposures and the Onset of Alzheimer's Disease Pathologies
(2014)It is been estimated that nearly 5 million Americans suffer from Alzheimer's Disease (AD), making finding its cause one of medicine's top priorities. It has long been known that genetics plays a major role in the development ... -
Investigating the role microRNAs play in the root-knot nematode Meloidogyne incognita’s viability, reproduction, and parasitism in cotton
(East Carolina University, 2023-04-25)Functions of four microRNAs (miRNAs), min-miR1, min-miR71, min-miR100a, and min-miR-124, were investigated in the parasitic nematode Meloidogyne incognita’s (M. incognita’s) overall behavior and mortality. M. incognita is ... -
Investigating the Role of CG8093 in Drosophila Female Germline Stem Cells
(East Carolina University, 2023-05-03)Cell division and differentiation are imperative for the maintenance of living organisms. Germ cells, which serve as the progenitor cells necessary to create oocytes and sperm, are maintained in many organisms by the ... -
Investigating the Role of CtBP in Colorectal Cancer
(2015-04-29)Recent studies in breast cancer tissue have demonstrated that C-terminal binding protein (CtBP) over-expression induces stem cell-like features and genome instability; whereas CtBP depletion or caloric restriction reverses ... -
Investigating the Role of Ecdysone Receptor in Germline to Somatic Cell Communication
(East Carolina University, 2023-12-04)Oogenesis requires complex coordination between both somatic and germ cell populations, relying on systemic signals such as hormones for proper oocyte production and formation. Drosophila melanogaster is an excellent model ...