Browsing Health Sciences Campus by Title
Now showing items 1380-1399 of 2643
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The Interaction of Caldesmon with the COOH Terminus of Actin
(East Carolina University, 1991-10-25)Caldesmon interacts with the NH2-terminal region of actin. It is now shown in airfuge centrifugation experiments that modification of the penultimate cysteine residue of actin significantly weakens its binding to caldesmon ... -
Interaction of memantine with ethanol consumption and dopaminergic function in high ethanol preferring rats
(East Carolina University, 2009)N-methyl-D-aspartate (NMDA) receptor antagonists have been reported to decrease ethanol consumption in rodents, but these drugs often produce adverse side effects. Memantine is a neuroprotective and low-affinity, ... -
Interactions of a Dopamine D Receptor Agonist with Glutamate NMDA Receptor Antagonists on the Volitional Consumption of Ethanol by the mHEP Rat
(2013-03)Stimulation of the dopamine D1 receptor is reported to cause the phosphorylation of DARPP-32 at the thre34 position and activates the protein. If intracellular Ca2+ is increased, such as after activation of the glutamate ... -
Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa
(East Carolina University, 2001-09-25)Pseudomonas aeruginosa is an opportunistic pathogen that controls numerous virulence factors through intercellular signals. This bacterium has two quorum-sensing systems (las and rhl), which act through the intercellular ... -
Interlaboratory Evaluation of Rodent Pulmonary Responses to Engineered Nanomaterials: The NIEHS Nano GO Consortium
(2013-05)Background: Engineered nanomaterials (ENMs) have potential benefits, but they also present safety concerns for human health. Interlaboratory studies in rodents using standardized protocols are needed to assess ENM ... -
Interprofessional collaborative project for the diagnosis, assessment, and treatment of contracted (frozen) shoulder
(2016-07-12)Contracted (frozen) shoulder (CFS) is a condition characterized by decreased active and passive shoulder range of motion and pain. The etiology of CFS is unknown and even the diagnostic terminology has evolved. Some risk ... -
Interprofessional obesity treatment: An exploration of current literature and practice
(2021)This exploratory exercise was to gain an understanding of current literature and practice regarding adult Interprofessional obesity treatment team practice. A synthesis of 87 articles and 9 websites and a qualitative ... -
Interrelated role of Notch signaling and mTORC pathways in prostate cancer cell survival and growth
(East Carolina University, 2014)Prostate cancer is currently the second highest leading cause of cancer death in men. Notch is a transmembrane receptor protein that is part of a signaling pathway necessary in the normal development of the prostate. ... -
Into the Trenches: Collaborating with Medical Students
(2017-10-23)Objective: After the successful implementation of a study room project to increase medical students’ use of the library’s physical spaces, the liaison librarian for the School of Medicine was challenged to increase medical ... -
The intracellular proteolytic fragment of CD44 alters CD44 function in chondrocytes
(East Carolina University, 2010)CD44 is an adhesion molecule involved in several biological functions and the primary receptor for hyaluronan (HA). In cartilage, CD44 participates in the interplay between cells and the extracellular matrix to fine tune ... -
Intraoperative Eye Care: A DNP Project
(2022-12-02)Corneal abrasions, while rare, are the most common optic injury that occurs in anesthesia practice, and they account for approximately 2-3% of all anesthesia malpractice suits. Corneal abrasions also cause intense discomfort ... -
Intratracheal instillation of silver nanoparticles exacerbates cardiac ischemia/reperfusion injury in male sprague-dawley rats
(East Carolina University, 2014)The uses of engineered nanomaterials have expanded in biomedical technology and consumer manufacturing. Exposure to particulate matter has been demonstrated to negatively influence cardiovascular health and expand myocardial ... -
Intravenously delivered graphene nanosheets and multiwalled carbon nanotubes induce site-specific Th2 inflammatory responses via the IL-33/ST2 axis
(2013)Carbon-based nanomaterials (CBN), such as graphene nanosheets (GNS) and multiwalled carbon nanotubes (MWCNT), have been proposed for potential nanomedicine applications such as biomedical devices and carriers for drug ... -
INTRINSIC EXERCISE CAPACITY ON HIND LIMB ARTERIAL LIGATION: DIFFERENTIAL IMPACT OF ACTIVE EXERCISE AND ANDROGEN SIGNALING ON POST-ISCHEMIC RECOVERY
(East Carolina University, 2018-12-21)Peripheral arterial disease (PAD) is a common disease that is frequently caused by atherosclerosis and associated thrombosis, leading to a decrease in the blood supply to the lower extremities. PAD has various treatment ... -
Introducing the global medical community to the information presented at local scientific conferences through nephrology blogs
(2012-12)An increasing number of healthcare providers author medical blogs (bloggers) to educate the public and fellow physicians. Traditionally, many bloggers have assumed that readers are most interested in information presented ... -
Introduction of a Novel Quick Reference Guide for Certified Registered Nurse Anesthetists to Assist in Perioperative Fire Prevention: A Quality Improvement Project
(2021-12-07)Perioperative fires are traumatizing events that may lead to patient and staff morbidity and mortality. CRNAs are in a unique position for monitoring, assessing, and intervening to prevent perioperative fires yet fire ...