Browsing Health Sciences Campus by Title
Now showing items 1486-1505 of 2641
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Localization and Characterization of a 7.3-kDa Region of Caldesmon Which Reversibly Inhibits Actomyosin ATPase Activity
(East Carolina University, 1992-08-15)Cleavage of caldesmon with chymotrypsin yields a series of fragments which bind both calmodulin and actin and inhibit the binding of myosin subfragments to actin and the subsequent stimulation of ATPase activity. Several ... -
A Long Helix from the Central Region of Smooth Muscle Caldesmon
(East Carolina University, 1991-07-25)The central region of smooth muscle caldesmon is predicted to form α-helices on the basis of its primary structure. We have isolated a fragment (CT54) that contains this region. The hydrodynamic properties and the electron ... -
Long Noncoding RNA Expression Signatures of Metastatic Nasopharyngeal Carcinoma and Their Prognostic Value
(2015)Long noncoding RNAs (lncRNAs) have recently been found to play important roles in various cancer types. The elucidation of genome-wide lncRNA expression patterns in metastatic nasopharyngeal carcinoma (NPC) could reveal ... -
Long-term effect of insulin on glucose transport and insulin binding in cultured adipocytes from normal and obese humans with and without non-insulin-dependent diabetes.
(East Carolina University, 1987-10)We have tested the hypothesis that in vitro exposure of insulin- resistant adipocytes with insulin results in improved insulin action. A primary culture system of adipocytes from obese subjects with ... -
Long-Term Mortality of 306,868 Patients with Multi-Vessel Coronary Artery Disease: CABG versus PCI
(2013-08)Background Several randomized controlled trials (RCT) have reported no difference in long-term mortality between coronary artery bypass grafting (CABG) and percutaneous coronary intervention (PCI). The purpose of this ... -
Lots to know about benefits, risks of zinc
(2022-06-29)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column is about use of zinc supplementation for covid and supporting the immune system. Discussed are some of the benefits and risks ... -
Low adenosine agent, composition, kit and method for treatment of airway disease
(1999-11-30)An oligonucleotide which is antisense to a mRNA encoding a polypeptide involved in airway disease(s) contains up to three adenosines per every 21 nucleotide a method of treating airway disease in a subject in need of such ... -
Low adenosine anti-sense oligonucleotide agent, composition, kit and treatments
(2000-02-24)A composition comprises a nucleic acid comprising an oligo anti-sense to a target such as polypeptide(s) associated with an ailment afflicting lung airways, genes and mRNAs encoding them, genomic and mRNA flanking regions, ... -
Low adenosine anti-sense oligonucleotide, compositions, kit and method for treatment of airway disorders associated with bronchoconstriction, lung inflammation, allergy(ies) and surfactant depletion
(2000-10-26)An in vivo method of selectively delivering a nucleic acid to a target gene or mRNA comprises the topical admistration, e.g. to the respiratory system, of a subject of a therapeutic amount of an oligonucleotide that is ... -
Lower Extremity Strength and Mechanics During Jumping in Women With Patellofemoral Pain
(2009)Context: Lower extremity (LE) weakness might be associated with altered mechanics during weight bearing in subjects with patellofemoral pain syndrome (PFPS). Objective: To analyze LE strength, mechanics, and the association ... -
Lumbee women breast cancer survivors stories: understanding the experience
(East Carolina University, 2009)The purpose of this interpretive study was to understand the experiences of Lumbee women breast cancer survivors from the text of their oral stories about their life events related to surviving breast cancer. Lumbees, the ... -
Lyme Disease Pathogenesis
(2021) -
Lymphocytic hypophysitis.
(East Carolina University, 1994-05)LYMPHOCYTIC HYPOPHYSITIS is an unusual disorder that nearly exclusively affects women; fewer than 50 cases have been reported in the literature. The present case also is unusual because a normal computed tomographic (CT) ... -
Macrophage Regulation in the Murine Inflammatory Response
(East Carolina University, 2018-08-30)The development of acute and chronic liver disease is a complex condition involving the dysregulation of hepatic metabolism and the accumulation of critical immune cells; specifically, the recruitment and activation of ... -
Make sure multi-vitamin delivers what you need.
(2023-07-19)This is a weekly Q and A newspaper column under the byline of Dr. Kathy Kolasa. Today's column answers two questions. First are multi vitamins delivered through a gummy as good as those in a pill. The second was about ...