Browsing Health Sciences Campus by Title
Now showing items 1587-1606 of 2645
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Microglial dysfunction as an early susceptibility to Alzheimer's disease: the exacerbating role of developmental toxicity
(East Carolina University, 2017-07-25)The association between perturbations to neuroimmune development and susceptibility to adult neurodegenerative diseases, like Alzheimer's disease (AD), may undersore a putative pathogenic role for gradual microglial ... -
MICRONOME AND KSHV INFECTION: IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF CELLULAR MICRORNAS DURING VIRUS ENTRY
(East Carolina University, 2018-04-17)Kaposi's sarcoma-associated herpesvirus (KSHV), is the most recently identified human herpesvirus and causes a variety of human malignancies. KSHV is etiologically associated with Kaposi's sarcoma (KS), primary effusion ... -
MicroRNA profiling in the left atrium in patients with non-valvular paroxysmal atrial fibrillation
(2015-08)Background We aimed to identify the miRNA expression profiles in left atrial appendage, with the intention of identifying miRNAs that were significantly associated with non-valvular paroxysmal AF. Methods The RNA ... -
MicroRNA-431 regulates axon regeneration in mature sensory neurons by targeting the Wnt antagonist
(2013-10)MicroRNAs (miRNAs) are small, non-coding RNAs that function as key post-transcriptional regulators in neural development, brain function, and neurological diseases. Growing evidence indicates that miRNAs are also important ... -
the MIND diet handout
(2020-11-01)The 2 page handout was designed to help patients/clients visualize an eating approach emphasizing food found in reducing dementia risk and slowing cognitive decline. It is based on the book, "Diet for the Mind" by Martha ... -
A Minimally-Invasive Procedure for Sexing Young Zebra Finches
(East Carolina University, 2007-08-15)Zebra finches have been widely used to study neurobiology underlying vocal development. Because only male zebra finches learn song, efficient developmental use of these animals requires early determination of sex at ages ... -
Mirror gait retraining for the treatment of patellofemoral pain in female runners.
(http://www.journals.elsevier.com/clinical-biomechanics, 2012-12)BACKGROUND: Abnormal hip mechanics are often implicated in female runners with patellofemoral pain. We sought to evaluate a simple gait retraining technique, using a full-length mirror, in female runners with patellofemoral ... -
Missing in Action: A Mission to Investigate and Neutralize Book Loss
(2015-10-19)Objective: During the summer of 2014, Laupus Library at East Carolina University began investigating an increase in the number of items that were being reported as being “not on shelf” by staff and patrons. Due to a ... -
Mitochondrial H₂O₂ emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
(2009-03)High dietary fat intake leads to insulin resistance in skeletal muscle, and this represents a major risk factor for type 2 diabetes and cardiovascular disease. Mitochondrial dysfunction and oxidative stress have been ... -
Mitochondrial Respiratory Capacity and Content Are Normal in Young Insulin-Resistant Obese Humans
(2014-01)Considerable debate exists about whether alterations in mitochondrial respiratory capacity and/or content play a causal role in the development of insulin resistance during obesity. The current study was undertaken to ... -
Mixture modeling with applications in schizophrenia research
(East Carolina University, 2009-05-15)Finite mixture modeling, together with the EM algorithm, have been widely used in clustering analysis. Under such methods, the unknown group membership is usually treated as missing data. When the "complete data" ... -
: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification
(2014-09)The nematode Caenorhabditis elegans (C. elegans) offers a unique opportunity for biological and basic medical researches due to its genetic tractability and well-defined developmental lineage. It also provides an exceptional ... -
Modeling of Non-Small Cell Lung Cancer Volume Changes during CT-Based Image Guided Radiotherapy: Patterns Observed and Clinical Implications
(2013)Background. To characterize the lung tumor volume response during conventional and hypofractionated radiotherapy (RT) based on diagnostic quality CT images prior to each treatment fraction. Methods. Out of 26 consecutive ... -
Modeling survival in colon cancer: a methodological review
(East Carolina University, 2007-02-12)The Cox proportional hazards model is the most widely used model for survival analysis because of its simplicity. The fundamental assumption in this model is the proportionality of the hazard function. When this condition ...