Browsing Health Sciences Campus by Title
Now showing items 1703-1722 of 2641
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Nonreceptor Tyrosine Kinase c-Yes Interacts with Occludin during Tight Junction Formation in Canine Kidney Epithelial Cells
(East Carolina University, 2002-04)Occludin is an integral membrane protein that is tyrosine phosphorylated when localized at tight junctions. When Ca2 was depleted from the culture medium, occludin tyrosine phosphorylation was diminished from Madin-Darby ... -
Normative Velopharyngeal Data in Infants: Implications for Treatment of Cleft Palate
(2016)Identifying normative data related to velopharyngeal muscles and structures may have clinical significance for infants born with cleft palate, especially as they relate to selection of surgical intervention and post-surgical ... -
NORTH CAROLINA NURSES WITH SUBSTANCE USE DISORDER: A BIOPSYCHOSOCIAL EXPLORATION
(East Carolina University, 2021-04-27)Substance abuse has impacted society economically through increased healthcare costs and lost work productivity; however, the greatest impact is the loss of life. Healthcare professionals such as nurses, physicians, ... -
North Carolina's Pediatric Obesity Clinician Reference Guide and Tool Kit
(2009-07-27)This poster presents the tools developed by clinicians treating childhood obesity in North Carolina. The history of the development of these tools is outlined at the end of the accompanying abstract submission to the ... -
North Carolina's Plan to Address Obesity: Healthy Weight and Healthy Communities
(2013-02-07)This presentation describes the 2013-2020 NC Obesity Plan. Evidence based core behaviors are described as well as strategies for encouraging the adoption of those behaviors in worksites, health care and colleges and ... -
Notch 3 Affects Chemoresistance in Colorectal Cancer via DNA Base Excision Repair Enzymes
(East Carolina University, 2017-07-28)Approximately 1.2 million cases of colorectal cancer (CRC) arise each year, and 40-50% of CRC patients will reach metastasis. The Notch pathway is known to be dysregulated in CRC, and its relationship with DNA repair ... -
Notch Signaling Mediates Drug Resistance in Colorectal Cancer Cells via Effects on DNA Repair Proteins
(East Carolina University, 2016-07-25)Colorectal cancer (CRC) is the second leading cause of cancer deaths in the United States and the third most commonly diagnosed cancer in men and women. Despite tremendous progress in diagnosis, prevention, and treatment ... -
Notched Acoustic Stimulus and Tinnitus: A Treatment Intervention Using a Randomization Test Approach
(East Carolina University, 2014)Musical training has considerable effects on human brain plasticity and music listening has been investigated as a means of treating tinnitus. In a laboratory setting, tailor-made notched music has been shown to reduce ... -
Note taking skills using the LiveScribe pen: implications for college students diagnosed with learning disabilities
(East Carolina University, 2014)The purpose of this study was to examine whether the use of strategic note-taking with the LiveScribe© pen increased the quantity of idea units, quality of notes written down, and retention of information provided for ... -
A Novel A1 Adenosine Receptor Antagonist, L-97-1 [3-[2-(4-Aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], Reduces Allergic Responses to House Dust Mite in an Allergic Rabbit Model of Asthma
(East Carolina University, 2005-10)Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics. Adenosine produces bronchoconstriction in allergic rabbits, primates, and humans by activating A1 adenosine receptors (ARs). ... -
Novel autoinducer molecules and uses therefor
(2002-03-07)Novel bacterial quinolone signal molecules and, more particularly, pseudomonas quinolone signal ('PQS') molecules, e.g., 2-heptyl-3hydroxy-4-quinolone, and analogs and derivatives thereof are described, Therapeutic ... -
NOVEL BIOLOGICS PROMOTE STABLE EXPANSION OF REGULATORY CD25HIGH FOXP3+ T LYMPHOCYTES AS A MEANS FOR AN ADOPTIVE CELL-BASED IMMUNOTHERAPY
(East Carolina University, 2021-06-18)Autoimmune disease arises when a breakdown in immunological self-tolerance causes self-reactive tissue destruction. In Multiple Sclerosis (MS), myelin reactive CD4+ T cells initiate an immune attack on the myelin sheath ... -
Novel Combination of Sorafenib and Celecoxib Provides Synergistic Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer Cells
(2013)Molecular targeted therapy has shown promise as a treatment for advanced hepatocellular carcinoma (HCC). Sorafenib, a multikinase inhibitor, recently received FDA approval for the treatment of advanced HCC. However, although ... -
A novel DAG-dependent mechanism links PKCa and Cyclin B1 regulating cell cycle progression
(2014-11)Through the years, different studies showed the involvement of Protein Kinase C (PKC) in cell cycle control, in particular during G1/S transition. Little is known about their role at G2/M checkpoint. In this study, using ... -
Novel diagnostic and analytical applications of benchtop time-domain NMR.
(East Carolina University, 2015)High-resolution nuclear magnetic resonance (NMR) spectroscopy is a powerful technique, yet practical application outside of the research laboratory has been limited due to the high cost and complexity of the instrumentation. ... -
The novel dual PI3K/mTOR inhibitor NVP-BGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells
(2015-07)Hepatocellular carcinoma (HCC) is one of the most common lethal human malignancies worldwide and its advanced status is frequently resistant to conventional chemotherapeutic agents and radiation. We evaluated the cytotoxic ... -
A Novel Educational Intervention: Improving Abdominal Pressure Strategies during Colonoscopy
(2021-07-23)Gastroenterology (endoscopy) procedures continue to increase in volume as innovative therapeutic endoscopy procedures are performed to meet the increasing demand for minimally invasive procedures. During endoscopy procedures, ...