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Effect of testosterone replacement or duration of castration on baroreflex bradycardia in conscious rats
(East Carolina University, 2005-03-30)
Background: In this study, we tested the hypothesis that 17β-estradiol contributes to testosterone-mediated restoration of baroreflex-mediated bradycardia in short-term (3 weeks) castrated rats. Further, a reported increase ...
Fesselin, a Synaptopodin-like Protein, Stimulates Actin Nucleation and Polymerization
(East Carolina University, 2001-11-27)
Fesselin is a proline-rich actin binding protein that has recently been isolated from smooth muscle [Leinweber, B. D., Fredricksen, R. S., Hoffman, D. R., and Chalovich, J. M. (1999) J. Muscle Res. Cell Motil. 20, 539–545]. ...
Quantum dot labeling of mesenchymal stem cells
(East Carolina University, 2007-11-07)
Background: Mesenchymal stem cells (MSCs) are multipotent cells with the potential to
differentiate into bone, cartilage, fat and muscle cells and are being investigated for their utility in
cell-based transplantation ...
Statins induce lethal effects in acute myeloblastic lymphoma cells within 72 hours
(East Carolina University, 2008-02)
HMG-CoA Reductase inhibitors (statins) induce apoptosis in acute myeloid leukemia (AML) cells in vitro; however, the concentrations associated with cell death in AML cells are higher than those clinically tolerated during ...
Pitt County Memorial Hospital Plays a Role in the Eat Smart Move More North Carolina Movement
(2009)
Pitt County Memorial Hospital is taking the "Journey to Excellence" and as part of that journey, is creating a culture of wellness. This paper describes those efforts as well as the criteria for healthy food. Data ...
Systematic review of diagnostic tests for vaginal trichomoniasis.
(East Carolina University, 2000)
Objective: To review critically and to summarize the evidence of diagnostic tests and culture media for the diagnosis of Trichomonas vaginitis. Methods: We performed a systematic review of literature indexed in MEDLINE of ...
Unique V3 Loop Sequence Derived from the R2 Strain of HIV-Type 1 Elicits Broad Neutralizing Antibodies
(East Carolina University, 2004-11)
DNA vaccines expressing the envelope (Env) of the human immunodeficiency virus type 1 (HIV-1) have been relatively ineffective at generating high-titer, long-lasting, neutralizing antibodies. In this
study, DNA vaccines ...
Crc Is Involved in Catabolite Repression Control of the bkd Operons of Pseudomonas putida and Pseudomonas aeruginosa
(East Carolina University, 2000-02)
Crc (catabolite repression control) protein of Pseudomonas aeruginosa has shown to be involved in carbon regulation of several pathways. In this study, the role of Crc in catabolite repression control has been studied in ...
Abraham Flexner and the black medical schools.
(East Carolina University, 2006-09)
"Abraham Flexner and the Black Medical Schools" first appeared in Beyond Flexner: Medical Education in the Twentieth Century, Barbara Barzansky and Norman Gevitz, eds. Copyright 1992 by Barbara Barzansky and Norman Gevitz. ...
PqsE Functions Independently of PqsR-Pseudomonas Quinolone Signal and Enhances the rhl Quorum-Sensing System
(East Carolina University, 2008-11)
Pseudomonas aeruginosa is an opportunistic pathogen that causes both acute and chronic infections in immunocompromised individuals. This gram-negative bacterium produces a battery of virulence factors that allow it to ...