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Solubility and Bioactivity of the Pseudomonas Quinolone Signal Are Increased by a Pseudomonas aeruginosa-Produced Surfactant
(East Carolina University, 2005-02)
Pseudomonas aeruginosa is a gram-negative bacterium that causes serious infections in immunocompromised individuals and cystic fibrosis patients. This opportunistic pathogen controls many of its virulence factors and ...
Regulation of Pseudomonas Quinolone Signal Synthesis in Pseudomonas aeruginosa
(East Carolina University, 2005-07)
Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic lung infections in cystic fibrosis patients and is a major source of nosocomial infections. This bacterium controls many virulence factors by using ...
Adaptations of Pseudomonas aeruginosa to the Cystic Fibrosis Lung Environment Can Include Deregulation of zwf, Encoding Glucose-6-Phosphate Dehydrogenase
(East Carolina University, 2005-11)
Cystic fibrosis (CF) patients are highly susceptible to chronic pulmonary disease caused by mucoid Pseudomonas aeruginosa strains that overproduce the exopolysaccharide alginate. We showed here that a mutation in zwf, ...
Comparison Of The Mismatch Negativity and A Differential Waveform Response
(East Carolina University, 2005)
A mismatch negativity response (MMN) and a new differential waveform were derived in an effort to evaluate a neural refractory or recovery effect in adult listeners. The MMN was elicited using oddball test runs in which ...
Identification and Characterization of Optimal Gene Expression Markers for Detection of Breast Cancer Metastasis
(East Carolina University, 2005-08)
Sentinel lymph node (SLN) status is highly predictive of
overall axillary lymph node involvement in breast cancer.
Historically, SLN-positive patients have undergone
axillary lymph node dissection in a second ...
A Quantitative Survey of Gravity Receptor Function in Mutant Mouse Strains
(East Carolina University, 2005-12)
The purpose of this research was to identify vestibular deficits in mice using linear vestibular evoked potentials (VsEPs). VsEP thresholds, peak latencies, and peak amplitudes from 24 strains with known genetic mutations ...
The Electronic Resources Librarian in the Health Sciences Library: An Emerging Role
(East Carolina University, 2005-02)
ABSTRACT. This article will address the evolution of collection development in the age of e-resources. According to results from a survey conducted by the authors, there are some emerging "best practices" for librarians ...
A Novel A1 Adenosine Receptor Antagonist, L-97-1 [3-[2-(4-Aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], Reduces Allergic Responses to House Dust Mite in an Allergic Rabbit Model of Asthma
(East Carolina University, 2005-10)
Adenosine, an important signaling molecule in asthma, produces bronchoconstriction in asthmatics. Adenosine produces bronchoconstriction in allergic rabbits, primates, and humans by activating A1 adenosine receptors (ARs). ...
Opsonized Virulent Brucella abortus Replicates within Nonacidic, Endoplasmic Reticulum-Negative, LAMP-1-Positive Phagosomes in Human Monocytes
(East Carolina University, 2005-06)
Cells in the Brucella spp. are intracellular pathogens that survive and replicate within host monocytes. Brucella maintains persistent infections in animals despite the production of high levels of anti-Brucellaspecific ...
The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes
(East Carolina University, 2005-11)
Brevenal is a nontoxic short-chain trans-syn polyether that competes with brevetoxin (PbTx) for the active site on voltage-sensitive sodium channels. The PbTxs are highly potent polyether toxins produced during blooms of ...