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Inhibition by rapamycin of ornithine decarboxylase and epithelial cell proliferation in intestinal IEC-6 cells in culture
(East Carolina University, 1997-02)
1 Induction of the enzyme ornithine decarboxylase (ODC) appears to be controlled primarily at the
level of ODC mRNA translation. The immunosuppressant drug, rapamycin, blocked the induction of
ODC in response to serum ...
Allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model
(East Carolina University, 1995-07)
The ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (XO)- inhibiting properties. Human myocardium how- ever, has exhibited low levels of XO ...
The effects of reading acceleration on reading comprehension and decoding accuracy in high school students with reading disorders.
(East Carolina University, 2012)
Reading disorders have been hypothesized to result from an asynchrony between speed of processing characteristics of auditory and visual systems involved in decoding. It is hypothesized that reading at faster rates can ...
Mast cells and the IL-33/ST2 axis are essential determinants of carbon nanotube toxicity
(East Carolina University, 2012)
The rise of nanomaterial use in a variety of applications, including biomedical imaging and drug delivery, has led to concern about the potentially hazardous impacts on human health. Mast cells are critical for innate and ...
Student retention in associate degree nursing programs in north carolina
(East Carolina University, 2013)
no
Effect of gender on auditory brainstem response latencies and thresholds to air-and bone-conducted clicks in newborn infants
(East Carolina University, 2001)
Objective: An examination of gender differences in auditory brainstem response (ABR) wave V latencies and thresholds to air-and bone- conducted clicks was undertaken with newborn infants. Design: Two hundred and two full-term ...
Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results.
(East Carolina University, 2001-10)
L-Arginine may be a conditionally essential amino acid in children and adolescents with sickle cell disease, particularly as required substrate in the arginine-nitric oxide pathway for endogenous nitrovasodilation and ...
An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects.
(East Carolina University, 1988-08)
We have developed an in vitro muscle preparation suitable for metabolic studies with human muscle tissue and have investigated the effects of obesity and non-insulin-dependent diabetes mellitus (NIDDM) on glucose transport. ...
Identification of E2F1 as a positive transcriptional regulator for delta-catenin
(East Carolina University, 2008-05-02)
Delta-Catenin is upregulated in human carcinomas. However, little is known about the potential transcriptional factors that regulate delta-catenin expression in cancer. Using a human delta-catenin reporter system, we have ...
Differences in reproductive risk factors for breast cancer in middle-aged women in Marin County, California and a sociodemographically similar area of Northern California
(East Carolina University, 2009-03-25)
Background: The Northern California county of Marin (MC) has historically had high breast cancer incidence rates. Because of MC's high socioeconomic status (SES) and racial homogeneity (non-Hispanic White), it has been ...