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The Effect of Noise Exposure on Auditory Threshold, Otoacoustic Emissions, and Electrocochleography
(East Carolina University, 2016-07-25)
Noise exposure is the second leading cause of acquired sensorineural hearing loss and is one of the most common occupational and environmental hazards. Examining changes in behavioral thresholds has long been the standard ...
Characterization of FtrABCD: a ferrous iron-specific transporter that is required for the virulence of Brucella abortus 2308 in mice
(East Carolina University, 2016-07-21)
Brucella strains are Gram-negative bacteria that cause abortion and infertility in their natural animal hosts resulting in extensive economic losses. Humans can acquire a chronic, debilitating febrile illness known as ...
A phenomenological investigation of Spanish-English bilingual supervisees’ experience in clinical supervision
(East Carolina University, 2016-07-20)
With a growing number of American households speaking languages other than English, the counseling profession must meet the counseling needs of non-English speaking clients. In turn, clinical supervisors and counselor ...
Variations in Craniofacial and Velopharyngeal Structures Among Individuals with 22q11.2 Deletion Syndrome
(East Carolina University, 2016-07-25)
22q11.2 deletion syndrome is the most common genetic cause of velopharyngeal dysfunction. Studies examining 22q11.2 deletion syndrome have thus far primarily focused on variations in the bony framework. Limited information ...
Molecular mechanisms of peripheral nerve regeneration: emerging roles of microRNAs
(2013-02)
MicroRNAs are small non-coding RNAs that suppress gene expression through target mRNA degradation or translation repression. Recent studies suggest that miRNA plays an important role in multiple physiological and pathological ...
Why Does Exercise “Trigger� Adaptive Protective Responses in the Heart?
(2015-05)
Numerous epidemiological studies suggest that individuals who exercise have decreased cardiac morbidity and mortality. Pre-clinical studies in animal models also find clear cardioprotective phenotypes in animals that ...
Control of Vascular Smooth Muscle Cell Growth by Connexin 43
(2012-06)
Connexin 43 (Cx43), the principal gap junction protein in vascular smooth muscle cells (VSMCs), regulates movement of ions and other signaling molecules through gap junction intercellular communication (GJIC) and plays ...
Enhanced Mitochondrial Superoxide Scavenging Does Not Improve Muscle Insulin Action in the High Fat-Fed Mouse
(2015-05)
Improving mitochondrial oxidant scavenging may be a viable strategy for the treatment of insulin resistance and diabetes. Mice overexpressing the mitochondrial matrix isoform of superoxide dismutase (sod2tg mice) and/or ...
Multilevel Discourse Processing Analyses in Adults with a Cognitive Impairment
(East Carolina University, 2016-12-13)
Participants with a cognitive impairment associated with Alzheimer's disease (AD) present with discourse impairments early within the disorder. These discourse impairment are associated with declines in episodic, semantic, ...