Browsing Brody School of Medicine by Title
Now showing items 1403-1422 of 1484
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Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy
(2013)INTRODUCTION: Two replicate randomized, placebo-controlled six-month trials (RCTs) and an open-label treatment extension (OLE) comprised the pegloticase development program in patients with gout refractory to conventional ... -
Total error shift patterns for daily CT on rails image-guided radiotherapy to the prostate bed
(2011)Background To evaluate the daily total error shift patterns on post-prostatectomy patients undergoing image guided radiotherapy (IGRT) with a diagnostic quality computer tomography (CT) on rails system. Methods A ... -
Traces of embryogenesis are the same in monozygotic and dizygotic twins: not compatible with double ovulation
(East Carolina University, 2009-06)Common knowledge of over a century has it that monozygotic and dizygotic twinning events occur by unrelated mechanisms: monozygotic twinning ‘splits’ embryos, producing anomalously re-arranged embryogenic asymmetries; ... -
Trajectories of Unsecured Debt and Health at Midlife
(2021-06-13) -
Transcriptional Activation of Bordetella Alcaligin Siderophore Genes Requires the AlcR Regulator with Alcaligin as Inducer
(East Carolina University, 2001-01)Genetic and biochemical studies have established that Fur and iron mediate repression of Bordetella alcaligin siderophore system (alc) genes under iron-replete nutritional growth conditions. In this study, transcriptional ... -
Transcriptional Analysis of the Bordetella Alcaligin Siderophore Biosynthesis Operon
(East Carolina University, 1998-02)The alc gene cluster of Bordetella pertussis includes three genes, alcA, alcB, and alcC, which are involved in alcaligin siderophore biosynthesis in response to iron starvation. The production of AlcA, AlcB, and AlcC in ... -
Transcriptional regulation of 'pqsR', a gene that encodes a regulator of quinolone signal synthesis and virulence in 'Pseudomonas aeruginosa'
(East Carolina University, 2015)The gram-negative bacterium 'Pseudomonas aeruginosa' is an opportunistic pathogen that frequently causes nosocomial infections and serious chronic lung infections in cystic fibrosis patients. During infection 'P. aeruginosa' ... -
The Transcriptional Regulator Np20 Is the Zinc Uptake Regulator in
(2013)Zinc is essential for all bacteria, but excess amounts of the metal can have toxic effects. To address this, bacteria have developed tightly regulated zinc uptake systems, such as the ZnuABC zinc transporter which is ... -
The Transfer Origin for Bacteroides Mobilizable Transposon Tn4555 Is Related to a Plasmid Family from Gram-Positive Bacteria
(East Carolina University, 1998-01)Conjugal transfer of Bacteroides mobilizable transposon Tn4555 was examined with an Escherichia coli-based assay system. It was shown that mobilization required the cis-acting oriTTn region and that the Tn4555 mobATn gene ... -
The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad.
(East Carolina University, 1997-03)The mouse hind footpad inoculation model has served as a standard laboratory system for the study of the neuropathogenesis of herpes simplex virus type 1 (HSV-1) infection. The temporal and spatial distribution of viral ... -
Transplant Coordinators' Perceived Impact of Availability of Multiple Generic Immunosuppression Therapies on Patients, Workload, and Posttransplant Maintenance Therapy
(2013)Background. No studies have evaluated the impact of multiple generic immunosuppression medications on transplant coordinators (TCs) and patients. Methods. A cross-sectional, multicenter online survey of TCs managing ... -
Transplantation and the Trauma Surgeon
(East Carolina University, 1990-11)The number of satisfactory vascular organs suitable for organ transplantation can be increased appreciably by a close working relationship between traumatologists and transplant surgeons. Benefits will derive from more ... -
Transplantation of GABAergic Neurons but not Astrocytes Induces Recovery of Sensorimotor Function in the Traumatically Injured Brain
(East Carolina University, 2007-04-16)Embryonic stem (ES) cells have been investigated in many animal models of injury and disease. However, few studies have examined the ability of pre-differentiated ES cells to improve functional outcome following traumatic ... -
Transvaginal evisceration progressing to peritonitis in the emergency department: a case report
(2011)Background Abdominal pain is a common complaint among emergency department patients, making it essential to identify those with life-threatening etiologies. We report on the rare finding of atraumatic transvaginal bowel ... -
Trends in esophageal cancer and body mass index by race and gender in the state of Michigan
(East Carolina University, 2009-06-23)Background: Adenocarcinoma of the esophagus has been increasing in incidence in the U.S. over the past several decades, particularly among white males. The factors driving the racial disparity in adenocarcinomas rates are ... -
A Tri-Modality Image Fusion Method for Target Delineation of Brain Tumors in Radiotherapy
(2014)Purpose To develop a tri-modality image fusion method for better target delineation in image-guided radiotherapy for patients with brain tumors. Methods A new method of tri-modality image fusion was developed, ...