Browsing Brody School of Medicine by Title
Now showing items 483-502 of 727
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On-Line Adaptive Radiation Therapy: Feasibility and Clinical Study
(2010)The purpose of this paper is to evaluate the feasibility and clinical dosimetric benefit of an on-line, that is, with the patient in the treatment position, Adaptive Radiation Therapy (ART) system for prostate cancer ... -
Opsonized Virulent Brucella abortus Replicates within Nonacidic, Endoplasmic Reticulum-Negative, LAMP-1-Positive Phagosomes in Human Monocytes
(East Carolina University, 2005-06)Cells in the Brucella spp. are intracellular pathogens that survive and replicate within host monocytes. Brucella maintains persistent infections in animals despite the production of high levels of anti-Brucellaspecific ... -
Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results.
(East Carolina University, 2001-10)L-Arginine may be a conditionally essential amino acid in children and adolescents with sickle cell disease, particularly as required substrate in the arginine-nitric oxide pathway for endogenous nitrovasodilation and ... -
Orchiectomy or androgen receptor blockade attenuates baroreflex-mediated bradycardia in conscious rats
(East Carolina University, 2006-01)Background: Previous studies have shown that testosterone enhances baroreflex bradycardia. Therefore, conscious unrestrained rats were used to investigate the role of the androgen receptor in the testosterone-mediated ... -
The ornithine decarboxylase gene odc is required for alcaligin siderophore biosynthesis in Bordetella spp.: putrescine is a precursor of alcaligin.
(East Carolina University, 1996-01)Chromosomal insertions defining Bordetella bronchiseptica siderophore phenotypic complementation group III mutants BRM3 and BRM5 were found to reside approximately 200 to 300 bp apart by restriction mapping of cloned genomic ... -
Osteomyelitis Infection of Mycobacterium marinum: A Case Report and Literature Review
(2014-12)Mycobacterium marinum (M. marinum) is a ubiquitous waterborne organism that grows optimally at temperatures around 30°C. It is a nontuberculous Mycobacterium found in nonchlorinated water with worldwide prevalence. It is ... -
Outcomes of Roux-en-Y gastric bypass surgery for severely obese patients with type 1 diabetes: a case series report
(2010)Roux-en-Y gastric bypass surgery (RYGB) reverses type 2 diabetes (DM2) in approximately 83% of patients with morbid or severe obesity. This procedure has been performed in small numbers of severely obese patients with type ... -
Outpatient Colonoscopy by Rural Family Physicians
(East Carolina University, 2005-03)PURPOSE Five percent of family physicians offer colonoscopy services, either in the office or the hospital, often in rural areas that have no gastroenterologist. Two previous large series have shown the quality and safety ... -
Overcoming resistance to molecularly targeted anticancer therapies: rational drug combinations based on EGFR and MAPK inhibition for solid tumours and haematologic malignancies
(East Carolina University, 2007-06)Accumulating evidence suggests that cancer can be envisioned as a "signaling disease", in which alterations in the cellular genome affect the expression and/or function of oncogenes and tumour suppressor genes. This ... -
Oxidative stress response in an anaerobe, Bacteroides fragilis: a role for catalase in protection against hydrogen peroxide.
(East Carolina University, 1996-12)Survival of Bacteroides fragilis in the presence of oxygen was dependent on the ability of bacteria to synthesize new proteins, as determined by the inhibition of protein synthesis after oxygen exposure. The B. fragilis ... -
Oxytocin Modulation of Zebra Finch Vocal Development
(East Carolina University, 2010)Autism spectrum disorder is associated with deficits in three main behavioral areas: social behaviors, repetitive behaviors, and language abnormalities. Accumulating evidence suggests a potential role for oxytocin signaling ... -
p53 and NGAL: dual regulatory roles in advanced prostate cancer
(East Carolina University, 2011)The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ... -
A Pacific Food Guide from the Children's Healthy Living PRogram
(2016-02)The paper describes the development of the Pacific Food Guide. The Food Guide includes fruits, vegetables, fish and animals not typically found in the US Food Guides but are consumed by individuals living int the Pacific. ... -
Participation in Community-Originated Interventions is Associated with Positive Changes in Weight Status and Health Behaviors in Youth
(2012-04-13)Purpose. To assess changes in children’s health behaviors and weight status after participation in community-originated interventions. ... -
Paternal diet and exercise epigenetically program energy expenditure and glucose metabolism in mouse offspring
(East Carolina University, 2014)It is currently estimated that a third of Americans suffer from metabolic syndrome, which is an obesogenic disease shown to increase risk for developing type 2 diabetes (T2DM) by five-fold (Diabetes Care, 2012). The ... -
Patient and Practice Perspectives on Strategies for Controlling Blood Pressure, North Carolina, 2010–2012
(2014)Introduction Patient and practice perspectives can inform development of team-based approaches to improving blood pressure control in primary care. We used a community-based participatory research approach to assess patient ... -
Patterns of Distress in African American Mothers of Preterm Infants
(East Carolina University, 2009-06)Objective: To examine inter-relationships among stress due to infant appearance and behavior in the NICU, parental role alteration stress in the NICU, depressive symptoms, state anxiety, posttraumatic stress symptoms, and ... -
Patterns of Pelvic Radiotherapy in Patients with Stage II/III Rectal Cancer
(2013)High-level evidence supports adjuvant radiotherapy for rectal cancer. We examined the influence of sociodemographic factors on patterns of adjuvant radiotherapy for resected Stage II/III rectal cancer. Methods. Patients ...