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Apparatus and method for measuring physiological characteristics of an intact trachea in vitro
(2011-03-15)
Apparatus and methods for measuring smooth muscles responses (relaxation and contraction), transepithelial potential difference, and/or transepithelial impedance of an intact trachea in vitro. In particular embodiments, ...
A SINGLE-CHAIN GMCSF-MOG TOLEROGENIC VACCINE EXPANDS MOG-SPECIFIC CD25+ FOXP3+ REGULATORY T CELLS THROUGH LOW-EFFICIENCY ANTIGEN RECOGNITION EVENTS TO INHIBIT EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS
(2019-12)
Previous studies showed that tolerogenic vaccines comprised of single-chain GMCSF-neuroantigen (NAg) fusion proteins inhibited experimental autoimmune encephalomyelitis (EAE) in rodents. The studies detailed here provide ...
DEVELOPMENT OF SMALL-MODELCULE INHIGITORS OF THE INTIATING PROTEASES, C1r AND C1s, OF THE CLASSICAL COMPLEMENT PATHWAY
(2019-12)
Complement is a proteolytic cascade that upon activation plays a key effector role in the innate immune system and acts to prime the adaptive immune response. During normal homeostatic events, complement is tightly regulated ...
MOLECULAR MECHANISM OF THE CYTOTOXIC AND IMMUNOSTIMULATORY ACTIVITY OF 15 DEOXY PROSTAMIDE J2: INVESTIGATION OF CHOP10 AND NFĸB SIGNALING IN COLON CANCER
(East Carolina University, 2019-08-13)
The endoplasmic reticulum (ER) stress pathway is a prominent regulator of cancer cell death and as a result, ER stress inducers are being exploited pharmacologically. Cytotoxic ER stress is typically regulated by the ...
Multi-spectral physiologic visualization (MSPV) using laser imaging methods and systems for blood flow and perfusion imaging and quantification in an endoscopic design
(2017-08-28)
Multispectral imaging systems are provided including a first light source having a first wavelength configured to image a sample; a second light source, different from the first light source, having a second wavelength, ...
In-ear hearing test probe devices and methods and systems using same
(2017-11-04)
A medical hearing testing method includes: inserting an in-ear test probe that is coupled to a hearing test adapter into an ear of a patient at a patient site; receiving device identification data at a web portal operating ...
Cytokines and neuroantigens for treatment of immune disorders
(2017-05-10)
The present invention provides methods of regulating an immunological disorder comprising administering to a subject an effective amount of (i) an autoimmune antigen in conjunction with (ii) an anti-inflammatory cytokine. ...
Methods, systems and computer program products for visualizing anatomical structures and blood flow and perfusion physiology using imaging techniques
(2016-04-21)
Methods for combining anatomical data and physiological data on a single image are provided. The methods include obtaining an image, for example, a raw near-infrared (NIR) image or a visible image, of a sample. The image ...