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Type.Cast: The Heart of Medicine (2017)
(2017)
An art and literary magazine published by the Brody School of Medicine, Division of Health Sciences. The magazine contains artwork and writings by Brody School of Medicine's medical students and others throughout the Health ...
TGF-β Signaling, Via Smad3, Mediates Notch Pathway-Induced Stemness and Epithelial to Mesenchymal Transition in Colon Cancer Cells
(East Carolina University, 2017-08-21)
Late stage colorectal cancer (CRC) remains a challenging disease to treat due to several factors including stemness and epithelial to mesenchymal transition (EMT). Dysfunctional signaling pathways in CRC contribute to these ...
Type. Cast : Edition XI Brody School of Medicine Art & Literary Magazine (2018)
(2018)
An art and literary magazine published by the Brody School of Medicine, Division of Health Sciences. The magazine contains artwork and writings by Brody School of Medicine's medical students and others throughout the Health ...
Impact of prostate cancer treatment on pelvic nerve injury and erectile function
(East Carolina University, 2018-07-17)
Following prostate cancer treatment, many men will experience urogenital side effects including erectile dysfunction (ED), a condition significantly affecting survivor quality of life. The cause of ED after treatment is ...
Embracing a plant-based diet. What is it and what's the evidence
(2017-05)
In this paper we present a case of a young health professional feeling peer pressure to become vegan. We also present a case of a vegan baby. We discuss nutrient of concerns for individuals restricting or eliminating animal ...
Purification and Partial Characterization of Relaxin and Relaxin Precursors from the Hamster Placenta
(East Carolina University, 1993-07)
Previous immunological studies have indicated that the molecular structure of hamster relaxin is
quite different from that of porcine relaxin. In the present study, hamster relaxin was purified from
placentas and ...
LOCAL ADMINISTRATION OF CARBON MONOXIDE INHIBITS NEOINTIMA FORMATION IN BALLOON INJURED RAT CAROTID ARTERIES
(2005)
Recent studies indicate that systemic induction of heme oxygenase-1 (HO-1), which oxidatively degrades heme into iron, biliverdin, and carbon monoxide (CO), or adenoviral-mediated gene transfer of HO-1 inhibits neointima ...
The Influence of Iron on Pseudomonas aeruginosa Physiology: A regulatory link between iron and quorum sensing
(East Carolina University, 2008-06-06)
In iron-replete environments, the Pseudomonas aeruginosa Fur (ferric uptake regulator) protein represses expression of two small regulatory RNAs encoded by prrF1 and prrF2. Here we describe the effects of iron and PrrF ...
Mechanism for Improved Insulin Sensitivity after Gastric Bypass Surgery
(East Carolina University, 2008-12)
Context: Surgical treatments of obesity have been shown to induce rapid and prolonged improvements in insulin sensitivity. Objective: The aim of the study was to investigate the effects of gastric bypass surgery and the ...
Restoration of insulin responsiveness in skeletal muscle of morbidly obese patients after weight loss. Effect on muscle glucose transport and glucose transporter GLUT4.
(East Carolina University, 1992-02)
A major defect contributing to impaired insulin action in human obesity is reduced glucose transport activity in skeletal muscle. This study was designed to determine whether the improvement in whole body glucose disposal ...