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Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma
(2012-08)
NECL-5 is involved in regulating cell–cell junctions, in cooperation with cadherins, integrins and platelet-derived growth factor receptor, that are essential for intercellular communication. Its role in malignant ...
Resveratrol Inhibits KSHV Reactivation by Lowering the Levels of Cellular EGR-1
(2012)
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Targeted therapy for hepatocellular carcinoma: novel agents on the horizon
(2012-03)
Hepatocellular carcinoma (HCC) is the most common liver cancer, accounting for 90% of primary liver cancers. In the last decade it has become one of the most frequently occurring tumors worldwide and is also considered to ...
Reuse of a previously transplanted kidney: does success come with a price?
(2012-10)
Longer wait times for deceased donor kidney transplant have prompted newer initiatives to expedite the process. Reuse of a previously transplanted kidney might be appropriate in certain circumstances. However, one must ...
Effects of robotic-assisted laparoscopic prostatectomy on surgical pathology specimens
(2012)
Background
Robotic-assisted laparoscopic prostatectomy (RALP) has greatly changed clinical management of prostate cancer. It is important for pathologists and urologists to compare RALP with conventional open radical ...
Time Course of Altered Sensitivity to Inhibitory and Excitatory Agonist Responses in the Longitudinal Muscle-Myenteric Plexus and Analgesia in the Guinea Pig after Chronic Morphine Treatment
(2012-01)
Tolerance that develops after chronic morphine exposure has been proposed to be an adaptive response that develops and decays over a defined time course. The present study examined the development of tolerance to the acute ...
Feasibility of image-guided radiotherapy based on helical tomotherapy to reduce contralateral parotid dose in head and neck cancer
(2012)
Background
To evaluate the feasibility of image-guided radiotherapy based on helical Tomotherapy to spare the contralateral parotid gland in head and neck cancer patients with unilateral or no neck node metastases.
Methods
A ...
A Community-Driven Approach to Identifying “Winnable� Policies Using the Centers for Disease Control and Prevention’s Common Community Measures for Obesity Prevention
(2012)
Federally funded, community-based participatory research initiatives encourage the development and implementation of obesity prevention policies. In 2009, the Centers for Disease Control and Prevention (CDC) published the ...
Hypothermia in trauma patients: predicting the big chill
(2012)
Physicians commonly ignore hypothermia, an often-underappreciated event associated with mortality in trauma patients, in general due to its prevalence and belief that it is secondary to the injury itself (secondary ...