Browsing Open Access by Title
Now showing items 187-206 of 866
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Deletion of Macrophage Vitamin D Receptor Promotes Insulin Resistance and Monocyte Cholesterol Transport to Accelerate Atherosclerosis in Mice
(2015)Intense effort has been devoted to understanding predisposition to chronic systemic inflammation because it contributes to cardiometabolic disease. We demonstrate that deletion of the macrophage vitamin D receptor (VDR) ... -
Delineation and mapping of coastal shark habitat within a shallow lagoonal estuary
(2018-04-12)Estuaries function as important nursery and foraging habitats for many coastal species, including highly migratory sharks. Pamlico Sound, North Carolina, is one of the largest estuaries in the continental United States and ... -
Desiccation tolerance in Acinetobacter baumannii is mediated by the two-component response regulator BfmR
(2018-10-11)For the opportunistic pathogen Acinetobacter baumannii, desiccation tolerance is thought to contribute significantly to the persistence of these bacteria in the healthcare environment. We investigated the ability of A. ... -
Design of a prospective, multicenter, global, cohort study of electromagnetic navigation bronchoscopy
(2016-04-26)Background: Electromagnetic navigation bronchoscopy (ENB) procedures allow physicians to access peripheral lung lesions beyond the reach of conventional bronchoscopy. However, published research is primarily limited to ... -
Designing the Learning Experiences in Serious Games: The Overt and the Subtle—The Virtual Clinic Learning Environment
(2018-06-29): Serious Games are becoming more common in the educational setting and must pass muster with both students and instructors for their learning experience and knowledge building. The Virtual Clinic Learning Environment ... -
Developing Concept Enriched Models for Big Data Processing Within the Medical Domain
(2020-07)Within the past few years, the medical domain has endeavored to incorporate artificial intelligence, including cognitive computing tools, to develop enriched models for processing and synthesizing knowledge from Big Data. ... -
Developing high performance concrete for precast/prestressed concrete industry
(2019-10-10)High performance concrete (HPC) is a new class of concrete that has superior characteristics compared to conventional concrete. Despite of its superior characteristics, HPC is not widely used in local and international ... -
Development of a Mobile Health Intervention to Promote Papanicolaou Tests and Human Papillomavirus Vaccination in an Underserved Immigrant Population: A Culturally Targeted and Individually Tailored Text Messaging Approach
(2019-06-06)Background: Disparities in cervical cancer incidence and mortality signify the need for intervention efforts targeting Korean American immigrant women. Objective: The purpose of this study was to demonstrate how a ... -
Development of a new diabetes medication self-efficacy scale and its association with both reported problems in using diabetes medications and self-reported adherence
(2016-06-07)Background: Although there are several different general diabetes self-efficacy scales, there is a need to develop a self-efficacy scale that providers can use to assess patient’s self-efficacy regarding medication use. ... -
Development of a RAD-Seq Based DNA Polymorphism Identification Software, AgroMarker Finder, and Its Application in Rice Marker-Assisted Breeding
(2016-01-22)Rapid and accurate genome-wide marker detection is essential to the marker-assisted breeding and functional genomics studies. In this work, we developed an integrated soft- ware, AgroMarker Finder (AMF: http://erp.novelb ... -
Development of a robust nonlinear pitch angle controller for a redesigned 5MW wind turbine blade tip
(2019-01-23)Power in wind turbines are traditionally controlled by varying the pitch angle at high wind speeds in region 3 of the wind turbine operation. The pitch angles controllers are normally driven by electrical or hydraulic ... -
Development of improved therapeutic mesothelin-based vaccines for pancreatic cancer
(2018-02-23)Pancreatic cancer is the 5th leading cause of cancer deaths, and there are no effective treatments. We developed a poxvirus platform vaccine with improved immunogenicity and inserted the mesothelin gene to create an ... -
Diabetic muscle infarction: A rare complication of long-standing and poorly controlled diabetes mellitus
(2011-10-09)Objective. To report a case of diabetic muscle infarction (DMI), a rare complication of long-standing poorly controlled diabetes mellitus. Methods. We describe a case of a 45-year-old male with an approximately 8-year ... -
Diet-induced muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin α<inf>2</inf>β <inf>1</inf>in mice
(2011)OBJECTIVE: The hypothesis that high-fat (HF) feeding causes skeletal muscle extracellular matrix (ECM) remodeling in C57BL/6J mice and that this remodeling contributes to diet-induced muscle insulin resistance (IR) through ... -
Differences in the carcinogenic evaluation of glyphosate between the International Agency for Research on Cancer (IARC) and the European Food Safety Authority (EFSA)
(2016-08)The International Agency for Research on Cancer (IARC) Monographs Programme identifies chemicals, drugs, mixtures, occupational exposures, lifestyles and per- sonal habits, and physical and biological agents that cause ... -
Differential Dopamine D1 and D3 Receptor Modulation and Expression in the Spinal Cord of Two Mouse Models of Restless Legs Syndrome
(2018-09-04)Restless Legs Syndrome (RLS) is often and successfully treated with dopamine receptor agonists that target the inhibitory D3 receptor subtype, however there is no clinical evidence of a D3 receptor dysfunction in RLS ... -
Differential expression of microRNAs during fiber development between fuzzless- lintless mutant and its wild-type allotetraploid cotton
(2017-01-31)Cotton is one of the most important textile crops but little is known how microRNAs regulate cotton fiber development. Using a well-studied cotton fiberless mutant Xu-142-fl, we compared 54 miRNAs for their expression ... -
Differential Post-Exercise Blood Pressure Responses between Blacks and Caucasians
(2016-04-13)Post-exercise hypotension (PEH) is widely observed in Caucasians (CA) and is associated with histamine receptors 1- and 2- (H1R and H2R) mediated post-exercise vasodilation. However, it appears that blacks (BL) may not ...