Browsing Open Access by Title
Now showing items 272-291 of 866
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Emerging roles for the pH-sensing G protein-coupled receptors in response to acidotic stress
(2015)Protons (hydrogen ions) are the simplest form of ions universally produced by cellular metabolism including aerobic respiration and glycolysis. Export of protons out of cells by a number of acid transporters is essential ... -
Endocrinologists’ Opinions of Diabetology as a Primary Care Subspecialty
(2018-04)This study was conducted to ascertain the opinions of endocrinologists about diabetes care as it relates to the health care provider workforce. A survey was administered to endocrinologists in the Planning Research in ... -
Engaging in Health Behaviors to Lower Risk for Breast Cancer Recurrence
(2013-01-11)Purpose While post-treatment breast cancer survivors face up to twice the cancer risk of the general population, modifiable health behaviors may somewhat reduce this risk. We sought to better understand health behaviors ... -
Enhanced Mitochondrial Superoxide Scavenging Does Not Improve Muscle Insulin Action in the High Fat-Fed Mouse
(2015-05)Improving mitochondrial oxidant scavenging may be a viable strategy for the treatment of insulin resistance and diabetes. Mice overexpressing the mitochondrial matrix isoform of superoxide dismutase (sod2tg mice) and/or ... -
Enhanced Recovery after Surgery in a Single High-Volume Surgical Oncology Unit: Details Matter
(2016-08)Benefits of ERAS protocol have been well documented; however, it is unclear whether the improvement stems from the protocol or shifts in expectations. Interdisciplinary educational seminars were conducted for all health ... -
Entropy Production Associated with Aggregation into Granules in a Subdiffusive Environment
(2018-08-30)We study the entropy production that is associated with the growing or shrinking of a small granule in, for instance, a colloidal suspension or in an aggregating polymer chain. A granule will fluctuate in size when the ... -
Environmental Health Hazardscapes
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Environmental Health Resilience
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Environmental risk factors for autism
(2011)Autism is a devastating childhood condition that has emerged as an increasing social concern just as it has increased in prevalence in recent decades. Autism and the broader category of autism spectrum disorders are among ... -
EPG5-related Vici syndrome: a paradigm of neurodevelopmental disorders with defective autophagy
(2016)Vici syndrome is a progressive neurodevelopmental multisystem disorder due to recessive mutations in the key autophagy gene EPG5. We report genetic, clinical, neuroradiological, and neuropathological features of 50 children ... -
EphrinA1-Fc attenuates myocardial ischemia/ reperfusion injury in mice
(2017-12-13)EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy car- diomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection ... -
Epigenetic re-wiring of breast cancer by pharmacological targeting of C-terminal binding protein
(2019-08-08)The C-terminal binding protein (CtBP) is an NADH-dependent dimeric family of nuclear proteins that scaffold interactions between transcriptional regulators and chromatin-modifying complexes. Its association with poor ... -
Epigenome-Wide Analyses Identify Two Novel Associations With Recurrent Stroke in the Vitamin Intervention for Stroke Prevention Clinical Trial Citation metadata
(2018-09-06)DNA methylation, a well-characterized epigenetic modification that is influenced by both environment and genetic variation, has previously been implicated in a number of complex diseases, including cardiovascular disease ... -
Erratum to: Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens
(2017-03-23)Erratum After the publication of this work [1] it was noticed that there was a typesetting error in figure 5 where two add- itional red lines were added in the sections “gene expres- sion profiles” and “transformed gene ... -
The errors of individualistic public health interventions: Denial of treatment to obese persons: Comment on “Denial of treatment to obese patients—the wrong policy on personal responsibility for health”
(2013-09-28)I agree entirely with Nir Eyal’s perspective that denying treatment to obese patients is morally wrong. However, the reasons for this belief differ in some ways from Eyal’s analysis. In this commentary, I will try to explain ... -
Esophageal perforation secondary to malignant gastric outlet obstruction: a case report
(2019-02-19)Background Esophageal perforation is a rare presenting sign of gastric cancer. To date, only nine case reports of this phenomenon have been previously published. Case presentation Esophageal perforation was diagnosed ... -
Essential role of proteasomes in maintaining self-renewal in neural progenitor cells
(2016-01-25)Protein turnover and homeostasis are regulated by the proteasomal system, which is critical for cell function and viability. Pluripotency of stem cells also relies on normal proteasomal activity that mitigates senescent ...