Browsing Open Access by Title
Now showing items 341-360 of 866
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Fractional Flow Reserve/ Instantaneous Wave-Free Ratio Discordance in Angiographically Intermediate Coronary Stenoses: An Analysis Using Doppler-Derived Coronary Flow Measurements
(2017-12-26)OBJECTIVES The study sought to determine the coronary flow characteristics of angiographically intermediate stenoses classified as discordant by fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR). BACKGROUND ... -
Frequency of Tongue Cleaning Impacts the Human Tongue Microbiome Composition and Enterosalivary Circulation of Nitrate
(2019-03-01)The oral microbiome has the potential to provide an important symbiotic function in human blood pressure physiology by contributing to the generation of nitric oxide (NO), an essential cardiovascular signaling molecule. ... -
From imitation to innovation: A study of China's drug R&D and relevant national policies
(2011)Research & Development (R&D) plays an increasingly important role in China's pharmaceutical industry. To gain a competitive edge in the global pharmaceutical market, the current national strategy of China forcefully pushes ... -
Functional and Comparative Genomics of Hoxa2 Gene cis-Regulatory Elements: Evidence for Evolutionary Modification of Ancestral Core Element Activity
(2016-03-26)Hoxa2 is an evolutionarily conserved developmental regulatory gene that functions to specify rhombomere (r) and pharyngeal arch (PA) identities throughout the Osteichthyes. Japanese medaka (Oryzias latipes) hoxa2a, like ... -
Functional Genomics of Wood Quality and Properties
(2003-11)Genomics promises to enrich the investigations of biology and biochemistry. Current advancements in genomics have major implications for genetic improvement in animals, plants, and microorganisms, and for our understanding ... -
Functional imaging of cognition in an old-old population: A case for portable functional near-infrared spectroscopy
(2017-10-12)In this study, functional near-infrared spectroscopy (fNIRS) was used to record brain activa- tion during cognitive testing in older individuals (88±6yo; N = 19) living in residential care communities. This population, ... -
Fungal-Host Interaction: Curcumin Modulates Proteolytic Enzyme Activity of Candida albicans and Inflammatory Host Response In Vitro
(2018-08-15)Current treatments for Candida albicans infection are limited due to the limited number of antifungal drugs available and the increase in antifungal resistance. Curcumin is used as a spice, food preservative, flavoring, ... -
FUSTr: a tool to find gene families under selection in transcriptomes
(2018-01-17)Background. The recent proliferation of large amounts of biodiversity transcriptomic data has resulted in an ever-expanding need for scalable and user-friendly tools capable of answering large scale molecular evolution ... -
A fuzzy feature fusion method for auto-segmentation of gliomas with multi-modality diffusion and perfusion magnetic resonance images in radiotherapy
(2018-02-19)The difusion and perfusion magnetic resonance (MR) images can provide functional information about tumour and enable more sensitive detection of the tumour extent. We aimed to develop a fuzzy feature fusion method for ... -
Gaining the PROMIS perspective from children with nephrotic syndrome: A Midwest pediatric nephrology consortium study
(2013-03-04)Abstract Background and objectives: Nephrotic syndrome (NS) represents a common disease in pediatric nephrology typified by a relapsing and remitting course and characterized by the presence of edema that can significantly ... -
Gemella Species Bacteremia and Stroke in an Elderly Patient with Respiratory Tract Infection
(2017-01-02)Gemella species are part of normal human flora. They are rarely associated with infections. As opportunistic pathogens, they can cause life-threatening infection in individuals with risk factors. We present an unusual case ... -
Gene Regulatory Evolution During Speciation in a Songbird
(2016-03-10)Over the last decade, tremendous progress has been made toward a comparative un- derstanding of gene regulatory evolution. However, we know little about how gene regulation evolves in birds, and how divergent genomes ... -
Genetic and Chemical Effects on Somatic and Germline Aging
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Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback
(2016-03)Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ... -
Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback
(2016)Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ... -
Genetic mapping of the female mimic morph locus in the ruff
(2013-11-20)Ruffs (Aves: Philomachus pugnax) possess a genetic polymorphism for male mating behaviour resulting in three permanent alternative male reproductive morphs: (i) territorial 'Independents', (ii) non-territorial 'Satellites', ... -
Genetic variation corroborates sub specific delimitation in the Namib fog-basking beetle, Onymacris unguicularis (Haag) (Tenebrionidae, Coleoptera)
(2013-11-20)The fog-basking beetle, Onymacris unguicularis (Haag, 1875), is currently listed as a polytypic form comprising two subspecies. A flightless substrate specialist, the beetleis endemic to vegetationless dunes in the Namib, ... -
Genome of Crucihimalaya himalaica, a close relative of Arabidopsis, shows ecological adaptation to high altitude
(2019-04-02)Crucihimalaya himalaica is a close relative of Arabidopsis with typical Qinghai–Tibet Plateau (QTP) distribution. Here, by combining short- and long-read sequencing technologies, we provide a de novo genome sequence of C. ... -
Genome sequence analysis of dengue virus 1 isolated in Key West, Florida
(2013-09-30)Dengue virus (DENV) is transmitted to humans through the bite of mosquitoes. In November 2010, a dengue outbreak was reported in Monroe County in southern Florida (FL), including greater than 20 confirmed human cases. The ... -
Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia
(2016-02-08)Craniofacial microsomia (CFM) is a rare congenital anomaly that involves immature derivatives from the first and second pharyngeal arches. The genetic pathogenesis of CFM is still unclear. Here we interrogate 0.9 million ...