Browsing Open Access by Title
Now showing items 852-866 of 866
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WalkMore: A randomized controlled trial of pedometer-based interventions differing on intensity messages
(2014-02-15)Pedometer-based programs have elicited increased walking behaviors associated with improvements in blood pressure in sedentary/low active postmenopausal women, a population at increased risk of cardiovascular disease. Such ... -
Water T2 as an early, global and practical biomarker for metabolic syndrome: an observational cross-sectional study
(2017-12-19)Background: Metabolic syndrome (MetS) is a highly prevalent condition that identifies individuals at risk for type 2 diabetes mellitus and atherosclerotic cardiovascular disease. Prevention of these diseases relies on ... -
A Waterfront View of Coastal Hazards: Contextualizing Relationships among Geographic Exposure, Shoreline Type, and Hazard Concerns among Coastal Residents
(2019-11-26)Coastal communities exist on the front lines of diverse natural hazards and the growing impacts of climate change. While traditional strategies for dealing with coastal hazards have often involved the hardening or armoring ... -
Weight-loss and exercise for communities with arthritis in North Carolina (we-can): design and rationale of a pragmatic, assessor-blinded, randomized controlled trial
(2017-02-22)Background: Recently, we determined that in a rigorously monitored environment an intensive diet-induced weight loss of 10% combined with exercise was significantly more effective at reducing pain in men and women with ... -
Wetland management strategies lead to tradeoffs in ecological structure and function
(2018-02-06)Anthropogenic legacy effects often occur as a consequence of land use change or land management and can leave behind long-lasting changes to ecosystem structure and function. This legacy is described as a memory in the ... -
What Do Program Directors Look for in an Applicant?
(2019-05-01)Program directors (PDs) are faced with an increasing number of applicants to emergency medicine (EM) and a limited number of positions. This article will provide candidates with insight to what PDs look for in an applicant. ... -
What factors influence older people’s intention to enrol in nursing homes? A cross-sectional observational study in Shanghai, China
(2018-09-05)Objectives Given the increasing need of long-term care and the low occupancy rate of nursing homes in Shanghai, this study attempts to explore what factors influence older people’s intention to enrol in nursing homes. Design ... -
Widespread brain reorganization perturbs visuomotor coordination in early glaucoma
(2019-10-02)Glaucoma is the world’s leading cause of irreversible blindness, and falls are a major public health concern in glaucoma patients. Although recent evidence suggests the involvements of the brain toward advanced glaucoma ... -
Widespread platinum anomaly documented at theYounger Dryas onset in North American sedimentary sequences
(2017-03-09)Previously, a large platinum (Pt) anomaly was reported in the Greenland ice sheet at the Younger Dryas boundary (YDB) (12,800 Cal B.P.). In order to evaluate its geographic extent, fire-assay and inductively coupled plasma ... -
WormGender – Open-Source Software for Automatic Caenorhabditis elegans Sex Ratio Measurement
(2015)Fast and quantitative analysis of animal phenotypes is one of the major challenges of current biology. Here we report the WormGender open-source software, which is designed for accurate quantification of sex ratio in ... -
Yttrium-90 radioembolization in patients with hepatocellular carcinoma who have previously received sorafenib
(2013-12-30)Purpose: Ytrrium-90 radioembolization (RE) is a locoregional therapy option for hepatocellular carcinoma (HCC). Sorafenib is a multikinase inhibitor used in HCC that can potentially affect the efficacy of RE by altering ... -
α-Klotho Expression in Mouse Tissues Following Acute Exhaustive Exercise
(2019-12-10)α-Klotho, a multifunctional protein, has been demonstrated to protect tissues from injury via anti-oxidation and anti-inflammatory effects. The expression of α-klotho is regulated by several physiological and pathological ... -
β-catenin nuclear translocation induced by HIF-1α overexpression leads to the radioresistance of prostate cancer
(2018-03-16)Hypoxia-inducible factor-1α (HIF-1α) is known to play crucial roles in tumor radioresistance; however, the molecular mechanisms responsible for the promotion of tumor radioresistance by HIF-1α remain unclear. β-catenin is ...