Browsing Open Access by Author "Virag, Jitka"
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EphrinA1-Fc attenuates myocardial ischemia/ reperfusion injury in mice
DuSablon, Augustin; Parks, Justin; Whitehurst, K’Shylah; Estes, H. Lynn; Chase, Robert; Vlahos, Eleftherios; Sharma, Uma; Wert, David; Virag, Jitka (2017-12-13)EphrinA1, a membrane-bound receptor tyrosine kinase ligand expressed in healthy car- diomyocytes, is lost in injured cells following myocardial infarction. Previously, we have reported that a single intramyocardial injection ... -
Use of Multifactorial Treatments to Address the Challenge of Translating Experimental Myocardial Infarct Reduction Strategies
Horton, Julie L.; Virag, Jitka (2019-03-15)Myocardial tissue damage that occurs during an ischemic event leads to a spiraling deterioration of cardiac muscle structural and functional integrity. Reperfusion is the only known efficacious strategy and is the most ...