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Comprehensive track-structure based evaluation of DNA damage by light ions from radiotherapy- relevant energies down to stopping
(2017-03-27)
Track structures and resulting DNA damage in human cells have been simulated for hydrogen, helium,
carbon, nitrogen, oxygen and neon ions with 0.25–256 MeV/u energy. The needed ion interaction cross sections have been ...
Contextual tumor suppressor function of T cell death-associated gene 8 (TDAG8) in hematological malignancies
(2017-12)
Background: Extracellular acidosis is a condition found within the tumor microenvironment due to inadequate blood perfusion, hypoxia, and altered tumor cell metabolism. Acidosis has pleiotropic effects on malignant progres‐ ...
Author Impact Metrics in Communication Sciences and Disorder Research
(2017-09)
Purpose: The purpose was to examine author-level impact metrics for faculty in the communication sciences and disorder research field across a variety of databases.
Method: Author-level impact metrics were collected for ...
Changes in zooplankton community, and seston and zooplankton fatty acid profiles at the freshwater/saltwater interface of the Chowan River, North Carolina
(2017-08-16)
The variability in zooplankton fatty acid composition may be an indicator of larval fish habitat quality as fatty acids are linked to fish larval growth and survival. We sampled an anadromous fish nursery, the Chowan River, ...
Bevacizumab in the treatment of NSCLC: patient selection and perspectives
(2017-12-14)
Non-small-cell lung cancer (NSCLC) represents about 85% of all lung cancers, and more than half of NSCLCs are diagnosed at an advanced stage. Chemotherapy has reached a plateau in the overall survival curve of about 10 ...
Analysis of the Germination of Individual Clostridium sporogenes Spores with and without Germinant Receptors and Cortex-Lytic Enzymes
(2017-10-25)
The Gram-positive spore-forming anaerobe Clostridium sporogenes is a significant cause of food spoilage, and it is also used as a surrogate for C. botulinum spores for testing the efficacy of commercial sterilization. C. ...
Circulating B cells in type 1 diabetics exhibit fewer maturation-associated phenotypes
(2017-10)
Although autoantibodies have been used for decades as diagnostic and prognostic markers in type 1 diabetes (T1D), further analysis of developmental abnormalities in B cells could reveal tolerance checkpoint defects that ...
Clinical assessment of medical students in the Emergency Department, A National Consensus Conference
(2017-01)
BACKGROUND
The clinical assessment of medical students in the emergency department (ED) is a highly variable process in which clerkship directors (CD) create and use institution-specific tools, many with unproven reliability ...
Beyond Beck's triad: A case report of cardiac tamponade in a “super-super” obese patient
(2017-06)
Cardiac tamponade is a medical emergency with various etiologies. Prompt recognition of the signs and symptoms of cardiac tamponade is critical but potentially full of challenge in clinical practice [1]. Here we report a ...
A novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women
(2017-03-02)
SNP rs7903146 in the Wnt pathway’s TCF7L2 gene is the variant most significantly associ- ated with type 2 diabetes to date, with associations observed across diverse populations. We sought to determine whether variants in ...