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How many steps/day are enough? For older adults and special populations
(2011-07-28)
Older adults and special populations (living with disability and/or chronic illness that may limit mobility and/or physical endurance) can benefit from practicing a more physically active lifestyle, typically by increasing ...
Is the genetic landscape of the deep subsurface biosphere affected by viruses?
(2011-11-09)
Viruses are powerful manipulators of microbial diversity, biogeochemistry, and evolution in the marine environment. Viruses can directly influence the genetic capabilities and the fitness of their hosts through the use of ...
Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy
(2011-07-01)
Elucidating the response of breast cancer cells to chemotherapeutic and hormonal based drugs is clearly important as these are frequently used therapeutic approaches. A signaling pathway often involved in chemo- and ...
HIV screening and awareness survey for pregnant women in a remote area in Xinjiang Uyghur autonomous region of China
(2011-11-30)
The number of people infected with human immunodeficiency virus (HIV) in China has increased in recent years. HIV screening for pregnant women was performed in a remote area in Xinjiang, as an effort to promote universal ...
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: Rationale and importance to inhibiting these pathways in human health
(2011-03-11)
The Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades are often activated by genetic alterations in upstream signaling molecules such as receptor tyrosine kinases (RTK). Integral components of these pathways, Ras, B-Raf, ...
Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: Two randomized controlled trials
(2011-08-17)
Context Patients with chronic disabling gout refractory to conventional urate-lowering therapy need timely treatment to control disease manifestations related to tissue urate crystal deposition. Pegloticase, monomethoxyp ...
Evidence for acquisition of virulence effectors in pathogenic chytrids
(2011-07-08)
Background
The decline in amphibian populations across the world is frequently linked to the infection of the chytrid fungus Batrachochytrium dendrobatidis (Bd). This is particularly perplexing because Bd was only recently ...
Conspecific brood parasitism in the tropics: An experimental investigation of host responses in common moorhens and American purple gallinules
(2011-08-03)
Species occupying a broad latitudinal range may show greater phenotypic plasticity in behavior than species with smaller ranges or more specific habitat requirements. This study investigates for the first time the occurrence ...
A multi-sensor approach to examining the distribution of total suspended matter (TSM) in the Albemarle-Pamlico Estuarine System, NC, USA
(2011)
For many coastal waters, total suspended matter (TSM) plays a major role in key biological, chemical and geological processes. Effective mapping and monitoring technologies for TSM are therefore needed to support research ...