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Genome-wide association study identifies multiple susceptibility loci for craniofacial microsomia
(2016-02-08)
Craniofacial microsomia (CFM) is a rare congenital anomaly that involves immature derivatives from the first and second pharyngeal arches. The genetic pathogenesis of CFM is still unclear. Here we interrogate 0.9 million ...
Genetic Architecture of Conspicuous Red Ornaments in Female Threespine Stickleback
(2016-03)
Explaining the presence of conspicuous female ornaments that take the form of male-typical traits has been a longstanding challenge in evolutionary biology. Such female ornaments have been proposed to evolve via both ...
Expert Consensus Guidelines for Stocking of Antidotes in Hospitals That Provide Emergency Care
(2018-03-01)
We provide recommendations for stocking of antidotes used in emergency departments (EDs). An expert panel representing diverse perspectives (clinical pharmacology, medical toxicology, critical care medicine, hematology/oncology, ...
Gene Regulatory Evolution During Speciation in a Songbird
(2016-03-10)
Over the last decade, tremendous progress has been made toward a comparative un- derstanding of gene regulatory evolution. However, we know little about how gene regulation evolves in birds, and how divergent genomes ...
Factors Affecting Patient Portal Use Among Low-Income Pregnant Women: Mixed-Methods Pilot Study
(2018-03-22)
Background: Patient portals offer patients personalized and secure Web access to their medical information and enable patients
to manage their health care online. However, there is a lack of information about patient ...
Fungal-Host Interaction: Curcumin Modulates Proteolytic Enzyme Activity of Candida albicans and Inflammatory Host Response In Vitro
(2018-08-15)
Current treatments for Candida albicans infection are limited due to the limited number of antifungal drugs available and the increase in antifungal resistance. Curcumin is used as a spice, food preservative, flavoring, ...
Exploring behaviors, treatment beliefs, and barriers to oral chemotherapy adherence among adult leukemia patients in a rural outpatient setting
(2018-11-29)
Objective:
Adherence to oral chemotherapy is essential for patients with chronic myeloid leukemia (CML) and multiple myeloma (MM) to remain in remission. Few studies have used a Likert-type scale to measure medication ...
FUSTr: a tool to find gene families under selection in transcriptomes
(2018-01-17)
Background. The recent proliferation of large amounts of biodiversity transcriptomic
data has resulted in an ever-expanding need for scalable and user-friendly tools capable
of answering large scale molecular evolution ...
Entropy Production Associated with Aggregation into Granules in a Subdiffusive Environment
(2018-08-30)
We study the entropy production that is associated with the growing or shrinking of a small granule in, for instance, a colloidal suspension or in an aggregating polymer chain. A granule will fluctuate in size when the ...
Comparative Study of the Roles of AhpC and KatE as Respiratory Antioxidants in Brucella abortus 2308
(2010-10)
Brucella strains are exposed to potentially toxic levels of H2O2 both as a consequence of their aerobic metabolism and through the respiratory burst of host phagocytes. To evaluate the relative contributions of the sole ...