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Patterns of pelvic radiotherapy in patients with stage II/III rectal cancer
(2013-10-02)
High-level evidence supports adjuvant radiotherapy for rectal cancer. We examined the influence of sociodemographic factors on patterns of adjuvant radiotherapy for resected Stage II/III rectal cancer. Methods. Patients ...
Social media guidelines and best practices - Recommendations from the council of residency directors (cord) social media taskforce
(2013-07-02)
Social media has become a staple of everyday life among over one billion people worldwide. A social networking presence has become a hallmark of vibrant and transparent communications. It has quickly become the preferred ...
Persistent akathisia masquerading as agitated depression after use of ziprasidone in the treatment of bipolar depression
(2013-04-04)
There has been increasing recognition that the second-generation antipsychotic drugs can produce extrapyramidal side effects. This case reports the development of severe akathisia in a patient being treated with ziprasidone ...
Theoretical aspects and modelling of cellular decision making, cell killing and information-processing in photodynamic therapy of cancer
(2013-09-03)
Background: The aim of this report is to provide a mathematical model of the mechanism for making binary fate decisions about cell death or survival, during and after Photodynamic Therapy (PDT) treatment, and to supply the ...
Deep Sequencing Reveals Transcriptome Re-Programming of Taxus × media Cells to the Elicitation with Methyl Jasmonate
(2013-04-30)
Background Plant cell culture represents an alternative source for producing high-value secondary metabolites including paclitaxel (Taxol®), which is mainly produced in Taxus and has been widely used in cancer chemotherapy. ...
Acidic tumor microenvironment and pH-sensing G protein-coupled receptors
(2013-12-05)
The tumor microenvironment is acidic due to glycolytic cancer cell metabolism, hypoxia, and deficient blood perfusion. It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection ...
Glycan Structures Contain Information for the Spatial Arrangement of Glycoproteins in the Plasma Membrane
(2013-09-06)
Glycoconjugates at the cell surface are crucial for cells to communicate with each other and the extracellular microenvironment. While it is generally accepted that glycans are vectorial biopolymers, their information ...
Genome sequence analysis of dengue virus 1 isolated in Key West, Florida
(2013-09-30)
Dengue virus (DENV) is transmitted to humans through the bite of mosquitoes. In November 2010, a dengue outbreak was reported in Monroe County in southern Florida (FL), including greater than 20 confirmed human cases. The ...
Genetic variation corroborates sub specific delimitation in the Namib fog-basking beetle, Onymacris unguicularis (Haag) (Tenebrionidae, Coleoptera)
(2013-11-20)
The fog-basking beetle, Onymacris unguicularis (Haag, 1875), is currently listed as a polytypic form comprising two subspecies. A flightless substrate specialist, the beetleis endemic to vegetationless dunes in the Namib, ...