Search
Now showing items 11-20 of 58
EARLY LIFE STRESS AND PHARMACEUTICAL POLLUTANTS: DEVELOPMENTAL TOXICITY OF EMERGING AQUATIC CONTAMINANTS IN A MODEL TERRESTRIAL SPECIES
(East Carolina University, 2019-07-18)
Trace amounts of pharmaceutical and personal care products are plaguing water sources around the globe, and with no current regulations, these emerging contaminants pose a threat to environmental and human health. While ...
MOLECULAR MECHANISM OF ELLAGIC ACID AND UROLITHIN A IN THE SUPPRESSION OF PROSTATE CANCER BY INFLUENCING THE p53-MDM2 PATHWAY
(East Carolina University, 2019-07-10)
Carcinoma of the prostate (CaP) is the most common cancer in men and the second leading cause of cancer-related death in men worldwide. Despite the available treatments for CaP including surgery and Androgen deprivation ...
Disrupted Adiponectin-Connexin43 Signaling Underlies Exacerbated Myocardial Dysfunction in Diabetic Female Rats
(East Carolina University, 2019-04-25)
The 2015 American Heart Association scientific statement has advocated for sex- specific research to understand the paradoxically higher sensitivity of women to type 2 diabetes mellitus (T2DM)-associated cardiovascular ...
EFFECTS OF CANNABIDIOL ON VOCAL LEARNING AND RECOVERY FROM CNS DAMAGE
(East Carolina University, 2019-06-19)
Cannabidiol (CBD), a non-euphorigenic compound derived from Cannabis, shows promise for improving recovery following cerebral ischemia and was recently effective for the treatment of childhood seizures caused by Dravet and ...
MOLECULAR MECHANISM OF THE CYTOTOXIC AND IMMUNOSTIMULATORY ACTIVITY OF 15 DEOXY PROSTAMIDE J2: INVESTIGATION OF CHOP10 AND NFĸB SIGNALING IN COLON CANCER
(East Carolina University, 2019-08-13)
The endoplasmic reticulum (ER) stress pathway is a prominent regulator of cancer cell death and as a result, ER stress inducers are being exploited pharmacologically. Cytotoxic ER stress is typically regulated by the ...