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Coevolutionary analysis of Appalachian Xystodesmid millipedes and their symbiotic Mesostigmatid mites
(East Carolina University, 2010)
Mites (Acari) form symbiotic relationships with many animal taxa including fish, amphibians, reptiles, birds, mammals, mollusks, and arthropods. They are frequently found living on millipedes, and it has often been ...
Multiple Factors Influence the Strength of Intraguild Interactions
(East Carolina University, 2011)
Species engaged in intraguild predation (IGP) not only compete for the same food resources but can also eat each other. In some cases, a predator species in a higher trophic position (i.e., a top predator) can eat a ...
Tumor Growth Induces Oxidative Clustered DNA Lesions Damage in Distant Mouse Tissue in vivo
(East Carolina University, 2010)
Our goal was to ascertain if DNA damage induced by oxidative stress is capable of being exploited as a precancerous or cancer biomarker. The specific DNA damage that we assessed was oxidatively induced non-DSB clustered ...
Cardiac and Mitochondrial Adaptations in Response to Aging and Doxorubicin in Rats Bred for Divergent Aerobic Capacities
(East Carolina University, 2012)
Doxorubicin (DOX) remains as one of the most widely prescribed and effective anticancer agents. A major limitation of the therapeutic effectiveness of the drug is the occurrence of irreversible, progressive, dose-dependent ...
The Effects of Gastrin and Hox-A1 on HT-29 Cell Proliferation
(East Carolina University, 2013)
Gastrin is a gastrointestinal peptide hormone synthesized in G cells and secreted in the antrum of the stomach. Though its primary role is to stimulate the secretion of gastric acid by parietal cells, it is also involved ...
DETECTION AND DISTRIBUTION OF THE AMPHIBIAN FUNGAL DISEASE CHYTRIDIOMYCOSIS IN PERUVIAN AMPHIBIANS
(East Carolina University, 2012)
Chytridiomycosis is an amphibian disease caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd;Longcore et al. 1999). This disease has been identified by the Amphibian Conservation Action Plan as one of the main ...
Effects of Nicotine on Caenorhabditis elegans survival, reproduction, and gene expressions : Development of an Invertebrate Animal Model for Drugs of Abuse
(East Carolina University, 2011)
Although much is known about the addictive effects of nicotine, the molecular mechanisms of nicotine-induced effects remain largely unclear. Specifically, little is known about the effects of nicotine on gene expression, ...
Drosophila Ctf4 is essential for genome stability and normal cell cycle progression
(East Carolina University, 2010)
Proper DNA replication and well-timed cell cycle progression are vital to the normal functioning of a cell. Precise coordination between these mechanisms' constituent proteins ensures their processivity while safeguarding ...
USE OF GENETIC TECHNIQUES TO IDENTIFY THE DIET OF COWNOSE RAYS, RHINOPTERA BONASUS, IN NORTH CAROLINA AND VIRGINIA : AN ANALYSIS OF SHELLFISH PREY ITEMS
(East Carolina University, 2013)
Cownose rays, Rhinoptera bonasus, are considered voracious predators on mollusks and have been implicated in the consumption of commercially important species of shellfish on the East Coast. Digestive tracts of the 32 ...
A Study of the Abundance, Distribution, and Grazing Effects of Zooplankton in the Chlorophyll Maximum (CMAX) of the Neuse River Estuary, North Carolina
(East Carolina University, 2012)
Phytoplankton tend to accumulate in distinct zones referred to as chlorophyll maxima, or CMAX. A pronounced CMAX occurs in the Neuse River Estuary (NRE), North Carolina, where as much as over 60% of the estuary's phytoplankton ...