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DISINTEGRIN-LIKE DOMAIN IN KSHV ENCODED gB IS A NECESSITY TO PROMOTE VIRUS LATENCY
(East Carolina University, 2011)
KSHV glycoprotein B (gB) is a lytic structural protein expressed on the envelope of mature virions and on the membrane of cells supporting lytic infection. Previous studies have identified that in addition to the role of ...
GILLNET CALIBRATION FOR SPINY DOGFISH ABUNDANCE ASSESSMENT
(East Carolina University, 2013)
Spiny dogfish (Squalus acanthias) is one of the most abundant species in the Northwest Atlantic however; the stocks collapsed in the late 1990s and were declared overfished April 3, 1998 by the Atlantic States Marine ...
Hypoxia and Serum Deprivation in Human Mesenchymal Stem Cells, and the Protective Role of Thymosin [Beta]-4
(East Carolina University, 2011)
Background: Current literature suggests nutrient deprivation and hypoxia affect human mesenchymal stem cell (hMSC) survival after cell transplantation. Wound-healing protein Thymosin [beta]-4 (T[beta]-4) has been shown ...
Spatio-Temporal Expression of Chondroitin Sulfate Antigens in Early Chick Pituitary and Thyroid
(East Carolina University, 2012)
The chondroitin sulfate antigens d1C4 and TC2 have been hypothesized to play a role in cartilage differentiation in the limb and early morphogenesis of the heart in chick embryos. The antibody d1C4 recognizes a native ...
Distribution Patterns of Juvenile Spotted Seatrout (Cynoscion nebulosus) and Red Drum (Sciaenops ocellatus) Along Shallow Beach Habitats in Pamlico River, North Carolina
(East Carolina University, 2012)
The association of juvenile spotted seatrout (Cynoscion nebulosus) and red drum (Sciaenops ocellatus) with Submerged Aquatic Vegetation (SAV) is well documented. However, their association with other estuarine habitats ...
Characterizing Environmental and Physicochemical Conditions in Nursery Areas of River Herring in Chowan River, North Carolina
(East Carolina University, 2012)
Anadromous fishes such as blueback herring Alosa aestivalis and alewife A. pseudoharengus, utilize sounds, rivers, and tributaries during spawning. Collectively known as river herring, these two ecologically important ...
Characterization of Two Novel Mutants of DNA Polymerase Delta in Drosophila melanogaster
(East Carolina University, 2011)
DNA is the genetic material for all living organisms which is constantly being unpackaged, replicated and repackaged. The replication of this genetic material involves numerous different proteins; however, DNA polymerase ...
Effect of Versican G1 Domain Overexpression on Hyaluronan, Hyaluronidase-2, and Synovial Joint Formation in the Embryonic Chick
(East Carolina University, 2013)
Versican, an extracellular chondroitin sulfate proteoglycan which binds hyaluronan, has been hypothesized to play a role in synovial joint formation in the chick embryo. Several studies have shown versican to be involved ...
Lateral Gene Transfer between Bacteria and Trichoderma reesei
(East Carolina University, 2012)
Lateral gene transfer (LGT) has played an important role in shaping the `tree of life'. It has promoted evolution by generating gene redundancies, which allow for more freedom in terms of allowed mutations in a genome, ...
Analysis of Complex DNA Damage Associated with Tumor Growth
(East Carolina University, 2012)
The innate response of a fully functioning immune system's ability to recognize and react to the growth of a tumor by releasing reactive oxygen species (ROS) may lead to chronic inflammation in many cases. This chronic ...