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Study of Morphology Based Cell Assay by Diffraction Imaging Flow Cytometry
(East Carolina University, 2015)
Development of an accurate and label-free method for single cell assay attracts intensive research efforts for its importance to cell biology research and clinicG14G7al applications. Flow cytometry is one of the most widely ...
Realistic optical cell modeling and diffraction imaging simulation for study of optical and morphological parameters of nucleus
(2016-01)
Coherent light scattering presents complex spatial patterns that depend on morphological and molecular features of biological cells. We present a numerical approach to establish realistic optical cell models for generating ...
Protection and Sensitization of Human Cells to Proton Radiation by Cerium Oxide Nanoparticles
(East Carolina University, 2017-07-17)
In radiation therapy for the treatment of cancer, there is demand for novel approaches that will improve tumor cell killing while protecting healthy tissue. One such approach that has shown considerable promise is the ...
Biophysical Mechanisms Mediating Fibrin Fiber Lysis
(2017-05-28)
The formation and dissolution of blood clots is both a biochemical and a biomechanical process. While much of the chemistry has been worked out for both processes, the influence of biophysical properties is less well ...
MODIFICATION OF CELL SURVIVAL RATES BY CERIUM OXIDE NANOPARTICLES FOR EXPOSURE TO PROTON RADIATION
(East Carolina University, 2017-05-03)
Radiation therapy is a well-established and widely used treatment for a variety of malignancies in the human body. Current radiotherapy methods most frequently use x-rays to deliver a lethal dose to tumors with sufficient ...
Fast Carbon-Ion and Proton Induced Electron Emission from Condensed-Phase Biological Targets
(East Carolina University, 2018-07-23)
Fast charged particles interact with matter through various ionization and excitation pathways that aren't fully understood. Predicting the effects of these interactions is vital in many fields such as radiation therapy, ...
Optimizing graphene oxide reduction via laser irradiation
(East Carolina University, 2017-01-04)
The present report discusses a single step method to reduce graphene oxide via laser irradiation. A computer numerically controlled laser engraver equipped with a 450nm laser diode was engineered to conduct this research. ...
A NEW ELECTRON SPECTROSCOPY SYSTEM FOR MEASURING ELECTRON EMISSION FROM FAST ION INTERACTIONS WITH ATOMIC, MOLECULAR, AND CONDENSED PHASE TARGETS
(East Carolina University, 2016-07-25)
A new electron spectroscopy system has been developed for measuring electron emission from gas and solid targets induced by fast ion impact. This system uses an ultrahigh-vacuum compatible cylindrical deflector analyzer, ...
Resolving power of diffraction imaging with an objective: a numerical study
(2017-05)
Diffraction imaging in the far-field can detect 3D morphological features of an object for its coherent nature. We describe methods for accurate calculation and analysis of diffraction images of scatterers of single and ...
A solution method determining the effect of spin upon gravitational effects in the surroundings of a black hole
(East Carolina University, 2017-12-12)
Using the theory of General Relativity and quasi-normal modes (QNMs) from the Teukolsky equation as a source of quasi-periodic oscillations (QPOs) from black holes provides information about black hole mass and spin. This ...