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Adamts9 is critical for the development of primary ovarian follicles
(East Carolina University, 2022-07-19)Adamts9 (a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 9) is an extracellular matrix metalloprotease that is highly evolutionarily conserved and critical for development in vertebrates. ... -
Adamts9 is critical for the development of primary ovarian follicles
(East Carolina University, 2022-07-19)Adamts9 (a disintegrin and metalloprotease with a thrombospondin type 1 motif, member 9) is an extracellular matrix metalloprotease that is highly evolutionarily conserved and critical for development in vertebrates. ... -
Adamts9 is necessary for ovarian development in zebrafish
(East Carolina University, 2020-05-04)Expression of adamts9 (A disintegrin and metalloprotease with thrombospondin type-1 motif, member 9) increases dramatically in the somatic cells surrounding oocytes during ovulation in vertebrates from zebrafish to human. ... -
ADAMTS9 IS NECESSARY FOR THE SEXUAL DEVELOPMENT OF FEMALE ZEBRAFISH
(East Carolina University, 2018-12-10)The ovary is a unique organ as it must cyclically alter its structure to accommodate the growth, development, and release of oocytes. The processes of oogenesis and ovulation requires structural modifications made to the ... -
Adapt & Overcome: Hypoxia Resistance is a Novel Phenotype of the Flexor Digitorum Brevis Skeletal Muscle
(East Carolina University, 2023-11-30)Skeletal muscle comprises the largest mammalian organ system by mass that enables movement, respiration, and thermogenesis. Each of these processes requires the presence of molecular oxygen (O2). Inadequate O2 bioavailability ... -
Adaptation in a Changing World: Evolutionary mechanisms of salt tolerance in a coastal amphibian
(East Carolina University, 2018-07-20)In order to predict evolutionary outcomes of environmental change on populations in nature, we need an improved understanding of the biological mechanisms that affect whether organisms will adapt to a changed environment. ... -
Adaptations of Pseudomonas aeruginosa to the Cystic Fibrosis Lung Environment Can Include Deregulation of zwf, Encoding Glucose-6-Phosphate Dehydrogenase
(East Carolina University, 2005-11)Cystic fibrosis (CF) patients are highly susceptible to chronic pulmonary disease caused by mucoid Pseudomonas aeruginosa strains that overproduce the exopolysaccharide alginate. We showed here that a mutation in zwf, ... -
Adaptations of the Hypothalamic Arcuate Nucleus in Response to Exercise and Hunger
(East Carolina University, 2018-05-02)The arcuate nucleus of the hypothalamus serves as a critical node for regulation of mammalian energy balance with the ability to sense the status of many organ systems and exert control over effector arms that potently ... -
Adaptive evolution of genes underlying schizophrenia
(East Carolina University, 2007-11-22)Schizophrenia poses an evolutionary-genetic paradox because it exhibits strongly negative fitness effects and high heritability, yet it persists at a prevalence of approximately 1% across all human cultures. Recent theory ... -
ADAPTIVE LEGACY: THE TRANSITION OF LIGHTHOUSES FROM SYMBOLS OF POLITICAL-ECONOMICAL STATEMENTS TO ICONS OF CULTURAL IDENTITY
(East Carolina University, 2017-05-03)Lighthouses on the eastern coast, North Carolina are iconic monuments of the scenic and historic landscape of the Outer Banks. The job for which these lighthouses were specifically designed was to aid mariners in navigating ... -
Adaptive responses to salinity stress across multiple life stages in anuran amphibians
(2017-08-01)Background In many regions, freshwater wetlands are increasing in salinity at rates exceeding historic levels. Some freshwater organisms, like amphibians, may be able to adapt and persist in salt-contaminated wetlands by ... -
Adding a Use Factor Measure to a Materials Allocation Plan for Books in an Academic Library
(2013-05)Tasked with re-working East Carolina University's Joyner Library materials allocation plan to better align it with current needs, two librarians, Lisa Barricella (Acquisitions) and Cindy Shirkey (Collection Development) ... -
Addressing COVID-19 Vaccine Hesitancy Using a Vaccine Decision Aid Tool
(2022-07-21)The COVID-19 pandemic highlighted health disparities among minority racial groups causing higher COVID-19 morbidity and mortality rates. Once the COVID-19 vaccine became available, Black/African American people had low ... -
Addressing Nurse Practitioner Role Transition During Doctor of Nursing Practice Education
(2023-07-13)Role transition is a known, multifactorial challenge new graduate advanced practice registered nurses (APRNs) face during their transition into practice causing reduced self-confidence, hindered role development, ...