Browsing by Issue Date
Now showing items 381-400 of 10629
-
Comparison of the exoS Gene and Protein Expression in Soil and Clinical Isolates of Pseudomonas aeruginosa
(East Carolina University, 2001-04)Exoenzyme S (ExoS) is translocated into eukaryotic cells by the type III secretory process and has been hypothesized to function in conjunction with other virulence factors in the pathogenesis of Pseudomonas aeruginosa. ... -
Ancient Genome Duplications Did Not Structure the Human Hox-Bearing Chromosomes
(East Carolina University, 2001-05)The fact that there are four homeobox (Hox) clusters in most vertebrates but only one in invertebrates is often cited as evidence for the hypothesis that two rounds of genome duplication by polyploidization occurred early ... -
Conference record of people, place, and progress: extended recovery on the coastal plain
(2001-05)This is the conference record for the People, Place, and Progress: Extended Recovery on the Coastal Plain conference held at East Carolina University in May 2001. -
The evolution of coloration and toxicity in the poison frog family (Dendrobatidae)
(East Carolina University, 2001-05-22)The poison frogs (family Dendrobatidae) are terrestrial anuran amphibians displaying a wide range of coloration and toxicity. These frogs generally have been considered to be aposematic, but relatively little ... -
Enhanced Avidity Maturation of Antibody to Human Immunodeficiency Virus Envelope: DNA Vaccination with gp120-C3d Fusion Proteins
(East Carolina University, 2001-06-10)DNA vaccination can elicit both humoral and cellular immune responses and can confer protection against several pathogens. However, DNA vaccines expressing the envelope (Env) protein of human immunodeficiency virus (HIV) ... -
Wurster's crown ligands
(2001-07-17)Wurster's crown ligands comprise a macrocyclic ligand such as a crown ether in which a hetero atom is substituted with a 1,4-phenylenediamine group. The phenylenediamine group is covalently bound to the macrocyclic ligand ... -
Simultaneous Positive and Purifying Selection on Overlapping Reading Frames of the tat and vpr Genes of Simian Immunodeficiency Virus
(East Carolina University, 2001-09)Tat-specific cytotoxic T cells have previously been shown to exert positive Darwinian selection favoring amino acid replacements of an epitope of simian immunodeficiency virus (SIV). The region of the tat gene encoding ... -
Interference with Pseudomonas quinolone signal synthesis inhibits virulence factor expression by Pseudomonas aeruginosa
(East Carolina University, 2001-09-25)Pseudomonas aeruginosa is an opportunistic pathogen that controls numerous virulence factors through intercellular signals. This bacterium has two quorum-sensing systems (las and rhl), which act through the intercellular ... -
Th1 Adjuvant N-Acetyl-d-Glucosamine Polymer Up-Regulates Th1 Immunity but Down-Regulates Th2 Immunity against a Mycobacterial Protein (MPB-59) in Interleukin-10-Knockout and Wild-Type Mice
(East Carolina University, 2001-10)Treatment of mice with heat-killed (HK) Mycobacterium bovis BCG or 1- to 10-μm chitin particles (nonantigenic N-acetyl-d-glucosamine polymers) is known to induce innate immune responses, including gamma interferon (IFN-γ) ... -
Oral citrulline as arginine precursor may be beneficial in sickle cell disease: early phase two results.
(East Carolina University, 2001-10)L-Arginine may be a conditionally essential amino acid in children and adolescents with sickle cell disease, particularly as required substrate in the arginine-nitric oxide pathway for endogenous nitrovasodilation and ... -
Robotic Surgical Training in an Academic Institution
(East Carolina University, 2001-10)Objective To detail robotic procedure development and clinical applications for mitral valve, biliary, and gastric reflux operations, and to implement a multispecialty robotic surgery training curriculum for both ... -
Fesselin, a Synaptopodin-like Protein, Stimulates Actin Nucleation and Polymerization
(East Carolina University, 2001-11-27)Fesselin is a proline-rich actin binding protein that has recently been isolated from smooth muscle [Leinweber, B. D., Fredricksen, R. S., Hoffman, D. R., and Chalovich, J. M. (1999) J. Muscle Res. Cell Motil. 20, 539–545]. ... -
Evidence for the presence of A1 adenosine receptors in the aorta of spontaneously hypertensive rats
(East Carolina University, 2001-12)1 Isolated aortic rings (endothelium-intact and -denuded) from spontaneously hypertensive (SHR) and Wistar-Kyoto (WKY) rats were used in this study to examine the vasoactive e ects of various adenosine analogues. 2 In ... -
Molecular phylogenetic evidence for a mimetic radiation in Peruvian poison frogs supports a Müllerian mimicry hypothesis.
(East Carolina University, 2001-12-07)Examples of Müllerian mimicry, in which resemblance between unpalatable species confers mutual benefit, are rare in vertebrates. Strong comparative evidence for mimicry is found when the colour and pattern of a single ...