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Now showing items 6023-6042 of 10631
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Mechanism of a Metal Catalyzed Reaction from a Computational Quantum Mechanical Perspective
(East Carolina University, 2016-05-02)A recent study reported an innovative approach to the synthesis of the pharmaceutical drug, Clinprost. The authors found that the introduction of a palladium catalyst into the reaction scheme helped reduce the overall ... -
Mechanisms controlling the acquisition of a cardiac phenotype by liver stem cells
(East Carolina University, 2007-03-06)The mechanisms underlying stem cell acquisition of a cardiac phenotype are unresolved. We studied early events during the acquisition of a cardiac phenotype by a cloned adult liver stem cell line (WB F344) in a cardiac ... -
Mechanisms for central cannabinoid receptor 1 evoked sympathoexcitation/pressor response in conscious rats
(East Carolina University, 2010)The main goal of the current study was to elucidate the molecular mechanisms implicated in central cannabinoid receptor 1 (CB1R)-evoked sympathoexcitation/pressor response. In pursuit of this goal, the candidate first ... -
Mechanisms Involved in the Cerebrovascular Dilator Effects of N-methyl-D-aspartate in Cerebral Cortex
(East Carolina University, 2007-11)Glutamate and its synthetic analogues N-methyl-D-aspartate (NMDA), kainate, and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) are potent dilator agents in the cerebral circulation. The close linkage between ... -
Mechanisms of germ cell development in Drosophila oogenesis.
(East Carolina University, 2018-07-17)Germ cell development requires interplay between factors that control cell fate and division. Early in their development, germ cells are an interconnected group of mitotically dividing cells. Key regulatory events then ... -
MECHANISMS OF LEFT VENTRICULAR REMODELING IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
(East Carolina University, 8/5/2020)Cardiac remodeling is composed of molecular, cellular, and interstitial changes in the cardiac tissue that affect the size, shape, and function of the heart. There are two types of cardiac remodeling: physiological and ... -
Mechanistic analysis of a synthetic inhibitor of the LasI quorum-sensing signal synthase
(2015-11)Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen responsible for many human infections. LasI is an acyl-homoserine lactone synthase that produces a quorum-sensing (QS) signal that positively regulates ... -
Mechanistic Strategies of Two-component Flavin-dependent Monooxygenases Involved in Sulfur Acquisition
(East Carolina University, 2023-08-09)All organisms require sulfur for diverse metabolic and physiological processes. Unlike mammals, bacteria are often deprived of sulfur in their natural habitat. To meet their sulfur needs, bacteria express various proteins ... -
Media and Fraud - Accounting and Accountability
(East Carolina University, 2019-12-12)Media can play a huge role in the decisions of individuals. However, how media coverage impacts individuals’ decisions in an accounting setting has not been addressed in the literature. My research question is: does media ... -
Media Bias and Public Opinion
(East Carolina University, 2019-05-03)This research focuses specifically on media outlets that are considered to be biased and partisan such as Fox News and MSNBC. Understanding how media might affect public opinion is important because it helps us understand ... -
Mediastinal neoplasms in patients with Graves disease: A possible link between sustained hyperthyroidism and thymic neoplasia'
(2012-07-23)BACKGROUND: Anterior mediastinal masses are a rare but well documented finding in Graves disease. The vast majority of these lesions represents benign thymic hypertrophy and regress after treatment of the hyperthyroidism. ... -
Mediastinal neoplasms in patients with Graves disease: a possible link between sustained hyperthyroidism and thymic neoplasia?
(2012)Background Anterior mediastinal masses are a rare but well documented finding in Graves disease. The vast majority of these lesions represents benign thymic hypertrophy and regress after treatment of the hyperthyroidism. ... -
The Mediating/Moderating Effects of Intrinsic Religiosity on the Gratitude-Health Relationship
(East Carolina University, 2009)The purpose of this study was to determine whether or not intrinsic religiosity is an effective mediator or moderator between gratitude and health in college-aged students. The sample population was 450 undergraduate ... -
Mediators of Change in Insulin Resistance with Weight-loss and Exercise Through the use of HOMA-IR
(East Carolina University, 2021-05-03)Purpose: It has been evidenced that the prevalence of obesity and type 2 diabetes (T2D) have significantly increased in the United States over the past two decades. However, previous studies have demonstrated that a reduction ... -
Medical and Household Characteristics Associated with Methicillin Resistant Nasal Carriage among Patients Admitted to a Rural Tertiary Care Hospital
(2013)Background Methicillin resistant Staphylococcus aureus (MRSA) poses a threat to patient safety and public health. Understanding how MRSA is acquired is important for prevention efforts. This study investigates risk ...