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Now showing items 6216-6235 of 10631
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Mitochondrial Diagnostics: A Multiplexed Assay Platform for Comprehensive Assessment of Mitochondrial Energy Fluxes
(2018-09-25)Chronic metabolic diseases have been linked to molecular signatures of mitochondrial dysfunction. Nonetheless, molecular remodeling of the transcriptome, proteome, and/or metabolome does not necessarily translate to ... -
MITOCHONDRIAL DNA VARIATION IN THE PITCHER PLANT FLY SARCOPHAGA SARRACENIAE: EXPLORING POSSIBLE INFLUENCES OF HOST SPECIFICITY AND GEOGRAPHIC STRUCTURING
(East Carolina University, 2019-05-03)North American pitcher plants (Sarracenia) are a recently evolved (~3 my) assemblage of 11 carnivorous species. Sarracenia pitchers also provide resources (food, shelter) for certain arthropods, including two genera of ... -
Mitochondrial H₂O₂ emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
(2009-03)High dietary fat intake leads to insulin resistance in skeletal muscle, and this represents a major risk factor for type 2 diabetes and cardiovascular disease. Mitochondrial dysfunction and oxidative stress have been ... -
Mitochondrial Oxidative Capacity In Human Skeletal Muscle: Association with Plasma Lactate Concentration
(East Carolina University, 2018-07-11)ABSTRACT Background: Metabolic disease is a growing concern for public health. Obesity and Type II Diabetes are an epidemic and a phenotype for insulin resistance in human skeletal muscle. A reduced mitochondrial function ... -
Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity
(2019-09-11)Exercise capacity is a strong predictor of all-cause mortality. Skeletal muscle mitochondrial respiratory capacity, its biggest contributor, adapts robustly to changes in energy demands induced by contractile activity. ... -
Mitochondrial Respiratory Capacity and Content Are Normal in Young Insulin-Resistant Obese Humans
(2014-01)Considerable debate exists about whether alterations in mitochondrial respiratory capacity and/or content play a causal role in the development of insulin resistance during obesity. The current study was undertaken to ... -
Mitsui-7, heat-treated, and nitrogen-doped multi-walled carbon nanotubes elicit genotoxicity in human lung epithelial cells.
(2019-10-07)Background: The unique physicochemical properties of multi-walled carbon nanotubes (MWCNT) have led to many industrial applications. Due to their low density and small size, MWCNT are easily aerosolized in the workplace ... -
A mixed method analysis of patients' complaints: Underpinnings of theory-guided strategies to improve quality of care
(2018-10-10)Purpose: Patients' complaints can be predictors of patient care quality and safety. Understanding patients' complaints could help healthcare organizations target the areas for improvements. The purpose of this study is ... -
Mixture modeling with applications in schizophrenia research
(East Carolina University, 2009-05-15)Finite mixture modeling, together with the EM algorithm, have been widely used in clustering analysis. Under such methods, the unknown group membership is usually treated as missing data. When the "complete data" ... -
Ml proteins from Mesorhizobium loti and MucR from Brucella abortus: an AT-rich core DNA-target site and oligomerization ability
(2017-11-17)Mesorhizobium loti contains ten genes coding for proteins sharing high amino acid sequence identity with members of the Ros/MucR transcription factor family. Five of these Ros/MucR family members from Mesorhizobium loti ... -
Mobile Assessment of the Dynamic Relationships between Experiential Avoidance, Mood, Stress, and Adherence in Cardiopulmonary Rehabilitation
(East Carolina University, 2020-06-22)Background: Despite the well-documented benefits of attending cardiopulmonary rehabilitation (CVPR) for many patients following acute cardiac or pulmonary events, adherence and completion rates remain suboptimal. Increased ... -
Mobile Device Management Policy
(2022-04-08)The use of mobile devices in the workplace has grown significantly over the years. Most adults do not leave home without their phones, laptops, tablets, or other portable media devices. With this expansion, there needed ...