Browsing Dissertations and Theses by Subject "Joints"
Now showing items 1-4 of 4
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Consequences of Reduced Versican Expression in Embryonic Chick Synovial Joint Development
(East Carolina University, 2012)The different mechanisms involved in vertebrate synovial joint development are actively being uncovered. A variety of studies have thus far discovered the involvement of several large molecules in the processes of joint ... -
Effect of Versican G1 Domain Overexpression on Hyaluronan, Hyaluronidase-2, and Synovial Joint Formation in the Embryonic Chick
(East Carolina University, 2013)Versican, an extracellular chondroitin sulfate proteoglycan which binds hyaluronan, has been hypothesized to play a role in synovial joint formation in the chick embryo. Several studies have shown versican to be involved ... -
SPATIAL EXPRESSION OF MATRIX AND MATRIX RECEPTOR PROTEINS IN THE DEVELOPING SYNOVIAL JOINT
(East Carolina University, 2013)Little is understood about the complex spatial and temporal molecular interactions necessary to form a fully functional synovial joint. Understanding molecular pathways and signaling within the developing joint continues ... -
VALIDATION OF CANDIDATE GENES IN RESPONSE TO VERSICAN MANIPULATION IN DEVELOPING SYNOVIAL JOINTS
(East Carolina University, 2012)Little is understood about the complex process of synovial joint formation in early limb development. It has been shown that versican is highly expressed in the extracellular matrix of these joints (Snow et al., 2005; ...