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Now showing items 191-200 of 221
Fesselin and caldesmon: natively unfolded proteins in smooth muscle regulation
(East Carolina University, 2010)
Dysregulation of smooth muscle contraction is linked to diseases such as atherosclerosis, asthma, hypertension, urinary incontinence, premature birth and others. The goal of this project is to contribute to our understanding ...
THE ROLE OF SDF-1[alpha] AS A VASCULOGENIC CHEMOKINE AND ENDOTHELIUM-ASSOCIATED CELL ADHESION MOLECULE FOR THE RECRUITMENT OF BONE MARROW-DERIVED PROGENITOR CELLS TO DEVELOPING TUMORS
(East Carolina University, 2010)
Tumor vascularization is an important control point in cancer progression and its inhibition is a promising approach to cancer therapy. Stromal-derived factor-1 alpha (SDF-1 alpha or CXCL12) is a chemoattractant for ...
Visual Perception in School-Aged Children: A Psychometric Study of the Correlation between Computer-based and Paper-based Scores on the Motor-Free Visual Perception Test, 3rd Edition
(East Carolina University, 2010)
Visual perceptual skills are often assessed using paper-and-pencil tests such as the Motor-Free Visual Perception Test, 3rd Edition (MVPT-3). A computer-based version of this assessment was independently developed. This ...
GIS BASED ARCHAEOLOGICAL SITE LOCATION MODELING IN PITT COUNTY, NORTH CAROLINA
(East Carolina University, 2010)
Archaeologists have employed Geographic Information Systems (GIS) software in the generation of predictive models for over thirty years. In the interest of creating a state wide predictive model, the North Carolina ...
Effects of the Pre-K Handwriting Without Tears Program on Handwriting Readiness Skills of Preschoolers with Pre-Writing Deficits in a Rural Eastern North Carolina Head Start Program
(East Carolina University, 2010)
The purpose of this study was to determine if preschoolers with pre-writing deficits who received additional small group exposure to the Pre-K Handwriting Without Tears® (HWT) - Get Set for School TM (GSS) program would ...
Prothymosin-Alpha : Features of the protein sequence that contribute to the anti-HIV Activity
(East Carolina University, 2010)
Prothymosin-alpha (ProT[alpha]) is a protein mainly located in the nucleus of the cells. Though its exact function is not known, it is believed to be involved in cell proliferation. The ability of this protein to inhibit ...
Sld5, A Subunit of the Heterotetrameric GINS Complex is Necessary for Normal Cell Cycle Progression and Genomic Stability
(East Carolina University, 2010)
Sld5 is one component of the GINS heterotetrameric complex essential to DNA replication. Specifically, GINS is known for its integral role during the G1 to S phase transition in the cell cycle. The GINS complex is comprised ...
Surfactant Assisted Electrospray Ionization Time of Flight Mass Spectrometry of Synthetic Polymers
(East Carolina University, 2010)
Synthetic polymers are complex mixtures which often require extensive characterization to determine chemical composition and structure. Mass spectrometric techniques have greatly enhanced the quantity, as well as the ...
EXPLORING THE BYSTANDER EFFECT FOLLOWING VERY LOW DOSE RADIATION
(East Carolina University, 2010)
Bystander effects are defined as the phenomenon in which unirradiated cells respond biologically when their neighbors are irradiated. The exact mechanisms of these cellular responses are still not known, especially in ...
WATER-SOLUBLE FLUORESCENT PH SENSORS BASED ON A DIARYLACETYLENE SCAFFOLD
(East Carolina University, 2010)
Intracellular pH plays an important role in many biological processes: receptor-mediated signal transduction, enzymatic activity, cell growth and death, ion transport and homeostasis, calcium regulation, endocytosis, ...