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Dynamic and Thermodynamic Mechanisms for the Onset of the Southeastern United States Convective Season
(East Carolina University, 2018-07-20)
The southeastern United States (SE US) receives ample precipitation year-round. In the winter, precipitation primarily comes from synoptic-scale baroclinic systems and cold fronts. Meanwhile, precipitation in the summer ...
EXAMINING THE IRON ISOTOPE GEOCHEMISTRY OF OLIVINE IN THE SKAERGAARD LAYERED MAFIC INTRUSION, EAST GREENLAND
(East Carolina University, 2018-07-24)
Despite reports of significant fractionation of iron isotopes occurring under magmatic and hydrothermal conditions, the mechanisms that cause and control fractionation in magmatic systems remain poorly understood. Previous ...
Pharmacological Regulation of Neural Circuit Formation in hIPSC-Derived Neurons and ‘Mini-Brains’
(East Carolina University, 2018-07-20)
Emerging evidence suggests that altered neural connectivity, particularly at the level of synaptic connections, contributes to the pathology of many neurodevelopmental and neurodegenerative diseases. For instance, post-mortem ...
SYSTEMATIC REVIEW OF LITERATURE USING TWITTER AS A TOOL
(East Carolina University, 2018-07-17)
Twitter has over 330 million active monthly users producing roughly 500 million Tweets per day, or 200 billion Tweets a year. Making this one of the largest human-generated opinion data collections. In addition to this ...
Fluorescent Derivatives of Prostamides: Tools for Studying Anti-Cancer Activity
(East Carolina University, 2018-07-23)
The endocannabinoid arachidonoyl ethanolamide (AEA) and prostaglandins derived from it selectively induce apoptosis in tumorigenic cell lines due to overexpression of COX-2. It is likely that a novel J-series prostamide, ...
Sense of Community in the Campus Recreation Setting: Fostering Community as a Strategy for Student Retention
(East Carolina University, 2018-07-20)
Institutions of higher education invest significant amounts of money building state-of-the-art campus recreation facilities in an environment where student fees and debt are increasing, while graduation and retention are ...
Characterizing Coastal Subenvironments with Modern Foraminiferal Assemblages: Bear Island and Bogue Banks, North Carolina
(East Carolina University, 2018-08-30)
North Carolina's coastline consists of an extensive barrier island system, with inlets acting as pathways for the exchange of sediment and water from estuarine and open ocean environments. Reconstructing past coastal changes ...
Holocene Paleoenvironmental Reconstruction of Depositional Environments on the Sunda Shelf, Southwest South China Sea, using a Multidisciplinary Approach
(East Carolina University, 2018-08-22)
The last glacial maximum, ca. 21,000 years ago, caused a fall in eustatic sea level of ca. 120 m below present. The low-gradient, shallow Sunda Shelf, Southeast Asia was subaerially exposed during this sea-level lowstand ...
Identification of Biomarkers in Non-Small Cell Lung Cancer Patients Treated with PD-1 Monoclonal Antibody Immunotherapy
(East Carolina University, 2018-08-22)
Cancer immunotherapy works by taking a patient's existing immune system and priming it to recognize cancer cells in order for immune cells to mount an effective response to the disease. This is a less invasive means of ...
Representations of Queen Victoria's Agency in Films and Miniseries
(East Carolina University, 2018-07-24)
This thesis examines the representations of Queen Victoria's agency through films and miniseries. For the selection of the films and miniseries had to be released in the twentieth century and present Queen Victoria in a ...